CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 10302 | ETCTN | Phase II Trial of Radium-223 Dichloride in Combination with Paclitaxel in Patients with Bone Metastatic Breast Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| A151804 | Alliance | Establishment of a National Biorepository to Advance Studies of Immune-Related Adverse Events | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-CC012CD | NRG | Managing Symptoms and Psychological Distress During Oral Anti-Cancer Treatment (SYMON) | Cancer Prevention and Control CIRB | Available to Open |
| S1607 | SWOG | A Phase II Study of Combining Talimogene Laherparepvec (T-VEC) (NSC-785349) and MK-3475 (Pembrolizumab) (NSC-776864) in Patients with Advanced Melanoma who have Progressed on ANTI-PD1/L1 Based Therapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10146 | ETCTN | Randomized phase 2 clinical trial of nab-paclitaxel + MEDI4736 (durvalumab) + tremelimumab + neoantigen vaccine vs. nab-paclitaxel + MEDI4736 (durvalumab) + tremelimumab in patients with metastatic triple negative breast cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| S1714 | SWOG | A Prospective Observational Cohort Study to Develop a Predictive Model of Taxane-Induced Peripheral Neuropathy in Cancer Patients | Cancer Prevention and Control CIRB | Available to Open |
| URCC-19178 | NCORP-University of Rochester Cancer Center | Optimizing Functional Outcomes of Older Cancer Survivors After Chemotherapy | Cancer Prevention and Control CIRB | Available to Open |
| 10480 | ETCTN | Phase Ib/II Study of EPA-based EphA2 Targeted Therapy for Patients with Metastatic Triple-Negative Inflammatory Breast Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| E1912 | ECOG | A Randomized Phase III Study of Ibrutinib (PCI- 32765)-based Therapy vs Standard Fludarabine; Cyclophosphamide; and Rituximab (FCR) Chemoimmunotherapy in Untreated Younger Patients with Chronic Lymphocytic Leukemia (CLL) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A011401 | Alliance | Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |