CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 10490 | ETCTN | Rapid Analysis and Response Evaluation of Combination Anti-neoplastic Agents in Rare Tumors (RARE CANCER) Trial: RARE 2 Talazoparib and Temozolomide | Adult CIRB - Early Phase Emphasis | Available to Open |
| MAY2016-08-01 | CP-CTNet_CLO-Mayo Clinic | A Pilot Study of MUC1 Vaccine in Current and Former Smokers at High Risk for Lung Cancer | Cancer Prevention and Control CIRB | Available to Open |
| S2209 | SWOG | A Phase III Randomized Trial for Newly Diagnosed Multiple Myeloma (NDMM) Patients Considered Frail or in a Subset of “Intermediate Fit” Comparing Upfront Three-Drug Induction Regimens Followed by Double- or Single-Agent Maintenance | Adult CIRB - Late Phase Emphasis | Available to Open |
| 9466 | ETCTN | Phase I/II study of dabrafenib, trametinib, and navitoclax in BRAF mutant melanoma (Phase I and II) and other solid tumors (Phase I only) | Adult CIRB - Early Phase Emphasis | Available to Open |
| 9825 | ETCTN | A Phase 2 Study of Olaparib and Cediranib for the Treatment of Recurrent Ovarian Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| ABTC-1802 | ABTC | A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10030 | ETCTN | A phase 1 study of blinatumomab in combination with checkpoint inhibitor(s) of PD-1 (nivolumab) or both PD-1 (nivolumab) and CTLA-4 (ipilimumab) in patients with poor-risk; relapsed or refractory CD19+ precursor B-lymphoblastic leukemia | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-LU006 | NRG | Phase III Randomized Trial of Pleurectomy/Decortication Plus Chemotherapy with or without Adjuvant Hemithoracic Intensity-Modulated Pleural Radiation Therapy (IMPRINT) for Malignant Pleural Mesothelioma (MPM) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1914 | SWOG | A Randomized Phase III Trial of Induction/Consolidation Atezolizumab (NSC #783608) + SBRT versus SBRT Alone in High Risk, Early Stage NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |
| ACCL1033 | COG | A Comprehensive Approach to Improve Medication Adherence in Pediatric ALL: A Group-wide Non-Therapeutic Study | Pediatric CIRB | Available to Open |