CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S0521 | SWOG | A Randomized Trial of Maintenance versus Observation for Patients with Previously Untreated Low and Intermediate Risk Acute Promyelocytic Leukemia (APL); Phase III | Adult CIRB - Late Phase Emphasis | Completed |
| EAA172 | ECOG-ACRIN | Phase 1/2 Study of Daratumumab, Bortezomib, Dexamethasone with or without Venetoclax in Relapsed/Refractory Multiple Myeloma with Assessment for t(11;14) Status | Adult CIRB - Late Phase Emphasis | Completed |
| AALL03B1 | COG | Classification of Acute Lymphoblastic Leukemia | Pediatric CIRB | Completed |
| E3200 | ECOG | Phase III Trial of Bevacizumab (NSC 704865); Oxaliplatin (NSC 266046); Fluorouracil and Leucovorin versus Oxaliplatin; Fluorouracil and Leucovorin versus Bevacizumab Alone in Previously Treated Patients with Advanced Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| 9875 | ETCTN | Phase 2 Study of AT13387 (onalespib) in ALK+ ALCL; MCL; and BCL-6+ DLBCL | Adult CIRB - Early Phase Emphasis | Completed |
| NRG-CC004 | NRG | Phase II Double Blind Dose Finding Trial of Bupropion Versus Placebo for Sexual Desire In Women With Breast or Gynecologic Cancer | Cancer Prevention and Control CIRB | Completed |
| CALGB-30607 | CALGB | Randomized; Phase III; Double-Blind Placebo-Controlled Trial of Sunitinib (NSC #736511; IND #74019) as Maintenance Therapy in Non-Progressing Patients Following an Initial Four Cycles of Platinum-Based Combination Chemotherapy in Advanced; Stage IIIB/IV Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ADVL1412 | COG | A Phase 1/2 Study of Nivolumab (IND# 124729) in Children; Adolescents; and Young Adults with Recurrent or Refractory Solid Tumors as a Single Agent and in Combination with Ipilimumab | Pediatric CIRB | Completed |
| ANBL1021 | COG | Feasibility/Phase II Study of hu14.18-IL2 immunocytokine + GM-CSF and Isotretinoin in Patients with Relapsed or Refractory Neuroblastoma: A Groupwide Phase II Study | Pediatric CIRB | Completed |
| 9653 | ETCTN | Phase II Trial of Gemcitabine-Eribulin (GE) in Cisplatin Ineligible Patients with Advanced or Unresectable Unrothelial Carcinoma of the Bladder | Adult CIRB - Early Phase Emphasis | Completed |