CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

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Study Number Lead Group Study Title CIRB Study Status
10273 ETCTN A Phase 1 Study of M3814 in combination with MEC in Patients with Relapsed or Refractory Acute Myeloid Leukemia Adult CIRB - Early Phase Emphasis Available to Open
A011502 Alliance A Randomized Phase III Double Blinded Placebo-Controlled Trial of Aspirin as Adjuvant Therapy for HER2 Negative Breast Cancer: The ABC Trial Adult CIRB - Late Phase Emphasis Available to Open
RTOG-1005 RTOG A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
ANHL04B1 COG Rare and Cutaneous Non-Hodgkin Lymphoma Registry Pediatric CIRB Available to Open
A071702 Alliance A Phase II Study of Checkpoint Blockade Immunotherapy in Patients with Somatically Hypermutated Recurrent Glioblastoma Adult CIRB - Late Phase Emphasis Available to Open
A031902 Alliance CASPAR - A Phase III Trial of Enzalutamide and Rucaparib as a Novel Therapy in First-Line Metastatic Castration-Resistant Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
AHOD03P1 COG Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study Pediatric CIRB Available to Open
PBTC-051 PBTC Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma Pediatric CIRB Available to Open
EAQ162CD ECOG-ACRIN Longitudinal Assessment of Financial Burden in Patients with Colon or Rectal Cancer Treated with Curative Intent Cancer Prevention and Control CIRB Available to Open
ARST2032 COG A Prospective Phase 3 Study of Patients with Newly Diagnosed Very Low-risk and Low-risk Fusion Negative Rhabdomyosarcoma Pediatric CIRB Available to Open
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