CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

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Study Number Lead Group Study Title CIRB Study Status
ACOSOG-Z6051 ACSOG A Phase III Prospective Randomized Trial Comparing Laparoscopic-assisted Resection Versus Open Resection for Rectal Cancer Adult CIRB - Late Phase Emphasis Available to Open
EA8143 ECOG-ACRIN A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) Adult CIRB - Late Phase Emphasis Available to Open
9914 ETCTN A Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors Adult CIRB - Early Phase Emphasis Available to Open
ANHL04B1 COG Rare and Cutaneous Non-Hodgkin Lymphoma Registry Pediatric CIRB Available to Open
EA9181 ECOG-ACRIN A Phase III Randomized Trial of Steroids +Tyrosine Kinase Inhibitor Induction with Chemotherapy or Blinatumomab for Newly Diagnosed BCR-ABL-positive Acute Lymphoblastic Leukemia in Adults Adult CIRB - Late Phase Emphasis Available to Open
10411 ETCTN Phase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST) Adult CIRB - Early Phase Emphasis Available to Open
10507 ETCTN A Phase 1/2 Study of the Bromodomain Inhibitor ZEN003694 in Combination with Etoposide/Platinum in Patients with NUT Carcinoma Adult CIRB - Early Phase Emphasis Available to Open
UWI20-00-01 CP-CTNet_CLO-University of Wisconsin A Phase II Trial of the Immunogenicity of a DNA Plasmid Based Vaccine (STEMVAC) Encoding Th1 Selective Epitopes from Five Antigens Associated With Breast Cancer Stem Cells (MDM2, YB1, SOX2, CDH3, CD105) in Participants with Early Stage Triple Negative Breast Cancer Cancer Prevention and Control CIRB Available to Open
10056 ETCTN A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma Adult CIRB - Early Phase Emphasis Available to Open
NRG-GY012 NRG A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combination of Cediranib/Olaparib in Women with Recurrent, Persistent or Metastatic Endometrial Cancer Adult CIRB - Late Phase Emphasis Available to Open
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