CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| RTOG-P-0011 | RTOG | Phase III Randomized Study of Adjuvant Therapy For High Risk PT2-3N0 Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| E1302 | ECOG | Phase III Randomized; Placebo-Controlled Trial of Docetaxel Versus Docetaxel Plus ZD1839 (Iressa; Gefitinib) in Performance Status 2 or Previously Treated Patients with Recurrent or Metastatic Head and Neck Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0219 | GOG | A Phase III; Randomized Trial of Weekly Cisplatin and Radiation Versus Cisplatin and Tirapazamine and Radiation in Stage IB2; IIA; IIB; IIIB; and IVA Cervical Carcinoma Limited to the Pelvis | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0286B | GOG | A Randomized Phase II/III Study Of Paclitaxel/Carboplatin/Metformin (NSC#91485) Versus Paclitaxel/Carboplatin/Placebo As Initial Therapy For Measurable Stage III Or IVA; Stage IVB; or Recurrent Endometrial Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY006 | NRG | A Randomized Phase II Trial of Radiation Therapy and Cisplatin Alone or in Combination with Intravenous Triapine in Women with Newly Diagnosed Bulky Stage IB2; Stage II; IIIB; or IVA Cancer of the Uterine Cervix or Stage II-IVA Vaginal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY016 | NRG | A Phase II Study of MK-3475 (Pembrolizumab) (NSC #776864) + Epacadostat (NSC #766086) in Recurrent Clear Cell Carcinoma of the Ovary | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI003 | NRG | Phase III Randomized Trial of Protons versus Photons for Hepatocellular Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA8185 | ECOG-ACRIN | Phase 2 Study of Bladder-SparIng ChemoradiatioN with MEDI4736 (Durvalumab) in clinical Stage 3, Node PosItive bladdeR cancEr (INSPIRE) | Adult CIRB - Late Phase Emphasis | Available to Open |
| E4201 | ECOG | A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy Versus Gemcitabine Alone in Patients with Localized; Unresectable Pancreatic Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| A021901 | Alliance | Randomized Phase II Trial of Lutetium Lu 177 Dotatate versus Everolimus in Somatostatin Receptor Positive Bronchial Neuroendocrine Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |