CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A051301 | Alliance | A Randomized Double-Blind Phase III Study of Ibrutinib During and Following Autologous Stem Cell Transplantation versus Placebo in Patients with Relapsed or Refractory Diffuse Large B-Cell Lymphoma of the Activated B-Cell Subtype | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2001 | SWOG | Randomized Phase II Clinical Trial of Olaparib + Pembrolizumab vs. Olaparib Alone as Maintenance Therapy in Metastatic Pancreatic Cancer Patients with Germline BRCA1 or BRCA2 Mutations | Adult CIRB - Late Phase Emphasis | Available to Open |
| AMC-115 | AMC | Use of a Screening Tool to Describe HIV-Related Cancer Burden and Patient Characteristics in the AIDS Malignancy Consortium | Adult CIRB - Late Phase Emphasis | Available to Open |
| E1A11 | ECOG | Randomized Phase III Trial of Bortezomib; LENalidomide and Dexamethasone (VRd) Versus Carfilzomib; Lenalidomide and Dexamethasone (CRd) Followed by Limited or Indefinite DURation Lenalidomide MaintenANCE in Patients with Newly Diagnosed Symptomatic Multiple Myeloma (ENDURANCE) | Adult CIRB - Late Phase Emphasis | Available to Open |
| GOG-0277 | GOG | A Phase III Randomized Trial of Gemcitabine (NSC# 613327) Plus Docetaxel (NSC# 628503) Followed by Doxorubicin (NCS# 123127) versus Observation for Uterus-Limited; High Grade Uterine Leiomyosarcoma | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GU008 | NRG | Randomized Phase III Trial Incorporating Abiraterone Acetate with Prednisone and Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer after Radical Prostatectomy | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY004 | NRG | Phase III Study Comparing Single-Agent Olaparib or the Combination of Cediranib and Olaparib to Standard Platinum-Based Chemotherapy in Women with Recurrent Platinum-Sensitive Ovarian; Fallopian Tube; or Primary Peritoneal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| CALGB-90203 | CALGB | A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk; Clinically Localized Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1011 | SWOG | A Phase III Surgical Trial to Evaluate the Benefit of a Standard Versus an Extended Pelvic Lymphadenectomy Performed at Time of Radical Cystectomy for Muscle Invasive Urothelial Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A051902 | Alliance | A Randomized Phase II Study of CHO(E)P vs CC-486-CHO(E)P vs Duvelisib-CHO(E)P in Previously Untreated CD30 Negative Peripheral T-Cell Lymphomas | Adult CIRB - Late Phase Emphasis | Available to Open |