CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 1030
Study Number Lead Group Study Title CIRB Study Status
CALGB-49907 CALGB A Randomized Trial of Adjuvant Chemotherapy with Standard Regimens; Cyclophosphamide; Methotrexate and Fluorouracil - (CMF) or Doxorubicin and Cyclophosphamide - (AC); Versus Capecitabine in Women 65 Years and Older with Node Positive or Node Negative Breast Cancer Adult CIRB - Late Phase Emphasis Completed
NRG-BN009 NRG Phase III Trial of Salvage Stereotactic Radiosurgery (SRS) or SRS + Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for First or Second Distant Brain Relapse after Upfront SRS with Brain Metastasis Velocity ≥4 Brain Metastases/Year Adult CIRB - Late Phase Emphasis Available to Open
E1302 ECOG Phase III Randomized; Placebo-Controlled Trial of Docetaxel Versus Docetaxel Plus ZD1839 (Iressa; Gefitinib) in Performance Status 2 or Previously Treated Patients with Recurrent or Metastatic Head and Neck Cancer Adult CIRB - Late Phase Emphasis Completed
RTOG-0214 RTOG A Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non-Small Cell Lung Cancer Adult CIRB - Late Phase Emphasis Completed
ABTC-1802 ABTC A Phase II Study of Binimetinib in Combination with Encorafenib in Adults with Recurrent BRAF V600-Mutated High-Grade Astrocytoma or other Primary Brain Tumor Adult CIRB - Late Phase Emphasis Available to Open
CALGB-90206 CALGB A Randomized Phase III Trial of Interferon Alfa-2B or Interferon Alfa-2B Plus Bevacizumab in Patients with Advanced Renal Carcinoma Adult CIRB - Late Phase Emphasis Completed
S1216 SWOG A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer Adult CIRB - Late Phase Emphasis Available to Open
EA6141 ECOG-ACRIN Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma Adult CIRB - Late Phase Emphasis Available to Open
EA5182 ECOG-ACRIN Randomized Phase III Study of Combination AZD9291 (osimertinib) and Bevacizumab versus AZD9291 (osimertinib) Alone as First-Line Treatment for Patients with Metastatic EGFR-Mutant Non-Small Cell Lung Cancer (NSCLC) Adult CIRB - Late Phase Emphasis Available to Open
A041701 Alliance A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy Adult CIRB - Late Phase Emphasis Available to Open
Displaying 1 - 10 of 1030