CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| RTOG-0825 | RTOG | Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide plus Bevacizumab versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-0848 | RTOG | A Phase II-R and A Phase III Trial Evaluating Both Erlotinib (Ph II-R) and Chemoradiation (Ph III) as Adjuvant Treatment for Patients with Resected Head of Pancreas Adenocarcinoma <br> | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-0920 | RTOG | A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-0924 | RTOG | Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1005 | RTOG | A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1010 | RTOG | A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-1016 | RTOG | Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1112 | RTOG | Randomized Phase III Study of Sorafenib Versus Stereotactic Body Radiation Therapy Followed by Sorafenib in Hepatocellular Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1115 | RTOG | Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 For Men with High Risk Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1216 | RTOG | Randomized Phase II/III Trial of Adjuvant Radiation Therapy with Cisplatin, Docetaxel-Cetuximab, or Cisplatin-Atezolizumab in Pathologic High-Risk, Squamous Cell Cancer of the Head and Neck | Adult CIRB - Late Phase Emphasis | Available to Open |