CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EAQ162CD | ECOG-ACRIN | Longitudinal Assessment of Financial Burden in Patients with Colon or Rectal Cancer Treated with Curative Intent | Cancer Prevention and Control CIRB | Available to Open |
| S0221 | SWOG | Phase III Trial of Continuous Schedule AC+G Vs. Q2 Week Schedule AC; Followed by Paclitaxel Given Either Every 2 Weeks or Weekly for 12 Weeks as Post-Operative Adjuvant Therapy in Node-Positive or High-Risk Node-Negative Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY033 | NRG | A Phase II Study of Androgen Receptor (AR) Inhibition by Darolutamide in Combination with Leuprolide Acetate and Exemestane in Recurrent Adult-Type Ovarian Granulosa Cell Tumor | Adult CIRB - Late Phase Emphasis | Available to Open |
| SCUSF-0901 | COG | SCUSF 0901 [ACCL0922] A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor | Pediatric CIRB | Available to Open |
| NRG-GI007 | NRG | Phase I Trial with Expansion Cohort of OBP-301 (Telomelysin™) and Definitive Chemoradiation for Patients with Locally Advanced Esophageal and Gastroesophageal Adenocarcinoma Who Are Not Candidates for Surgery | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10495 | ETCTN | Phase I Trial of DS-8201a (Trastuzumab Deruxtecan) in Combination with Neratinib in Solid Tumors with HER2 Alterations | Adult CIRB - Early Phase Emphasis | Available to Open |
| 10061 | ETCTN | A Phase 1 Study of MK-3475 (Pembrolizumab) in Combination with Recombinant Interleukin-12 in Patients with Solid Tumors | Adult CIRB - Early Phase Emphasis | Available to Open |
| EA5163 | ECOG-ACRIN | INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature-driven Analysis | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1216 | SWOG | A Phase III Randomized Trial Comparing Androgen Deprivation Therapy + TAK-700 with Androgen Deprivation Therapy + Bicalutamide in Patients with Newly Diagnosed Metastatic Hormone Sensitive Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NHLBI-MDS | ECOG | The National Myelodysplastic Syndromes (MDS) Study | Cancer Prevention and Control CIRB | Available to Open |