CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S1500 | SWOG | A Randomized; Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968]; Crizotinib [NSC #749005]; Savolitinib [NSC #785348]; and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S0200 | SWOG | A Phase III Randomized Study of Pegylated Liposomal Doxorubicin Plus Carboplatin Versus Carboplatin in Platinum-Sensitive Patients with Recurrent Epithelial Ovarian or Peritoneal Carcinoma After Failure of Initial Platinum-Based Chemotherapy | Adult CIRB - Late Phase Emphasis | Completed |
| S1823 | SWOG | A Prospective Observational Cohort Study To Assess miRNA 371 For Outcome Prediction in Patients With Newly Diagnosed Germ Cell Tumors | Cancer Prevention and Control CIRB | Available to Open |
| S1900C | SWOG | A Phase II Study of Talazoparib plus Avelumab in Patients with Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer Bearing Pathogenic STK11 Genomic Alterations (LungMAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1400 | SWOG | A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-Map) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2007 | SWOG | A Phase II Trial of Sacituzumab Govitecan (IMMU-132) (NSC #820016) for Patients with HER2-Negative Breast Cancer and Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2200 | SWOG | A Phase II Randomized Trial of Cabozantinib (NSC #761968) with or without Atezolizumab (NSC #783608) in Patients with Advanced Papillary Renal Cell Carcinoma (PAPMET2) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S0427 | SWOG | A Phase III Trial of Standard Fractionation Radiation and Concurrent Single Agent Cisplatin; with and without Docetaxel; Cisplatin; and 5-FluorouracilInduction Chemotherapy; in Patients with Advanced Oropharyngeal Squamous Cell Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| S1501 | SWOG | Prospective Evaluation of Carvedilol in Prevention of Cardiac Toxicity in Patients with Metastatic HER-2+ Breast Cancer; Phase III | Cancer Prevention and Control CIRB | Available to Open |
| S1609 | SWOG | DART: Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |