CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ANHL12P1 | COG | A Randomized Phase II Trial of Brentuximab Vedotin (SGN35; NSC# 749710) or Crizotinib (NSC#749005; commercially labeled) in Combination with Chemotherapy for Newly Diagnosed Patients with Anaplastic Large Cell Lymphoma (ALCL) IND # 117117 | Pediatric CIRB | Available to Open |
| ALTE07C1 | COG | Neuropsychological; Social; Emotional; and Behavioral Outcomes in Children with Cancer: A Groupwide Non-Therapeutic Study | Pediatric CIRB | Available to Open |
| ARST0531 | COG | Randomized Study of Vincristine; Dactinomycin and Cyclophosphamide (VAC) versus VAC Alternating with Vincristine and Irinotecan (VI) for Patients with Intermediate-Risk Rhabdomyosarcoma (RMS): A Groupwide Phase III Study | Pediatric CIRB | Completed |
| ACNS0232 | COG | Radiotherapy Alone vs. Chemotherapy Followed by Response-based Radiotherapy for Newly Diagnosed Primary CNS Germinoma: A Phase III Group-Wide Study | Pediatric CIRB | Completed |
| ADVL1521 | COG | A Phase 2 Study of the MEK inhibitor Trametinib (IND #119346, NSC# 763093) in Children with Relapsed or Refractory Juvenile Myelomonocytic Leukemia | Pediatric CIRB | Available to Open |
| AALL08B1 | COG | Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) | Pediatric CIRB | Available to Open |
| PBTC-N14 | PBTC | CSF Cell-free Tumor DNA (CSF cfDNA) Liquid Biopsies for Pediatric, Adolescent, and Young Adult Patients with Primary Brain Tumors | Pediatric CIRB | Available to Open |
| AALL0331 | COG | Standard Risk B-precursor Acute Lymphoblastic Leukemia (ALL): A Phase III Group-Wide Study | Pediatric CIRB | Completed |
| AGCT1531 | COG | A Phase 3 Study of Active Surveillance for Low risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors | Pediatric CIRB | Available to Open |
| PEPN21EHR/PBTC-N15 | Pediatric CITN | Pilot Study to Enable Electronic Laboratory Data Transfer into Medidata Rave | Pediatric CIRB | Completed |