CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A091304 | Alliance | A Phase I /Randomized Phase II Study of MLN0128 (TAK-228) vs. Pazopanib In Patients With Locally Advanced/Unresectable And/Or Metastatic Sarcoma | Adult CIRB - Early Phase Emphasis | Completed |
| RTOG-0522 | RTOG | A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation; Cisplatin and Cetuximab (C225) [Followed by Surgery for Selected Patients] For Stage III and IV Head and Neck Carcinomas<br> | Adult CIRB - Late Phase Emphasis | Completed |
| E2100 | ECOG | A Randomized Phase III Trial of Paclitaxel versus Paclitaxel plus Bevacizumab (rhuMAb VEGF) as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ANHL1131 | COG | Intergroup Trial for Children or Adolescents with B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients | Pediatric CIRB | Completed |
| RTOG-0412-SWOG-S0332 | RTOG | Phase III Randomized Trial of Preoperative Chemotherapy Versus Preoperative Concurrent Chemotherapy and Thoracic Radiotherapy Followed by Surgical Resection and Consolidation Chemotherapy in Favorable Prognosis Patients With Stage IIIA (N2) Non-Small Cell Lung Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| S0307 | SWOG | Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| GOG-0249 | GOG | A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed By Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk; Early Stage Endometrial Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| CALGB-90106 | CALGB | A Randomized Phase III Study of Paclitaxel; Ifosfamide and Cisplatin Versus Vinblastine; Ifosfamide and Cisplatin as Second-Line Therapy for Patients with Relapsed/Resistant Germ Cell Tumors | Adult CIRB - Late Phase Emphasis | Completed |
| ADVL1522 | COG | A Phase 2 Study of IMGN901 (Lorvotuzumab Mertansine; IND# 126953; NSC# 783609) in Children with Relapsed or Refractory Wilms Tumor; Rhabdomyosarcoma; Neuroblastoma; Pleuropulmonary Blastoma; Malignant Peripheral Nerve Sheath Tumor (MPNST) and Synovial Sarcoma | Pediatric CIRB | Completed |
| E4599 | ECOG | Randomized Phase II/III Trial of Paclitaxel plus Carboplatin With or Without Bevacizumab (NSC #704865) in Patients with Advanced Nonsquamous NSCLC | Adult CIRB - Late Phase Emphasis | Completed |