CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| AALL0331 | COG | Standard Risk B-precursor Acute Lymphoblastic Leukemia (ALL): A Phase III Group-Wide Study | Pediatric CIRB | Completed |
| ASCT2031 | COG | A Multi-Center, Phase 3, Randomized Trial of Matched Unrelated Donor (MUD) versus HLA-Haploidentical Related (Haplo) Myeloablative Hematopoietic Cell Transplantation for Children, Adolescents, and Young Adults (AYA) with Acute Leukemia or Myelodysplastic Syndrome (MDS) | Pediatric CIRB | Available to Open |
| AAML0121 | COG | "A Phase II Study of Amifostine In Children with Myelodysplastic Syndrome: A Group-wide Study" | Pediatric CIRB | Completed |
| ALTE05N1 | COG | Umbrella Long-Term Follow-Up Protocol | Pediatric CIRB | Available to Open |
| ARST0431 | COG | Intensive Multi-Agent Therapy; Including Dose-Compressed Cycles of Ifosfamide/Etoposide (IE) and Vincristine/Doxorubicin/Cyclophosphamide (VDC) for Patients with High-Risk Rhabdomyosarcoma: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| ACNS0224 | COG | A Phase I/II Study of Topotecan with G-CSF and Radiation Therapy In Children with Malignant Intrinsic Pontine Brainstem Gliomas of Childhood | Pediatric CIRB | Completed |
| ADVL1513 | COG | A Phase 1 Study of Entinostat; An Oral Histone Deacetylase Inhibitor; In Pediatric Patients with Recurrent or Refractory Solid Tumors; Including CNS Tumors and Lymphoma | Pediatric CIRB | Completed |
| ANBL17P1 | COG | A Pilot Induction Regimen Incorporating Chimeric 14.18 Antibody (ch14.18, dinutuximab) (NSC# 764038, IND# 4308) and Sargramostim (GM-CSF) for the Treatment of Newly Diagnosed High-Risk Neuroblastoma | Pediatric CIRB | Available to Open |
| ANHL1131 | COG | Intergroup Trial for Children or Adolescents with B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients | Pediatric CIRB | Completed |
| PBTC-061 | PBTC | Phase 2 Trial of G207 + 5 Gy Radiation for Children with High-Grade Gliomas | Pediatric CIRB | Available to Open |