CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A032101 | Alliance | A Phase 2 Trial of ADT Interruption in Patients Responding Exceptionally to AR-Pathway Inhibitor in Metastatic Hormone-Sensitive Prostate Cancer (MHSPC): A-DREAM | Adult CIRB - Late Phase Emphasis | Available to Open |
| GOG-0258 | GOG | A Randomized Phase III Trial of Cisplatin and Tumor Volume Directed Irradiation Followed by Carboplatin and Paclitaxel vs. Carboplatin and Paclitaxel for Optimally Debulked; Advanced Endometrial Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| AMC-107 | AMC | A Phase 2 Trial of Ixazomib for Kaposi Sarcoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| CALGB-30506 | CALGB | A Randomized Phase III Trial of Adjuvant Chemotherapy in Patients with Early Stage Non-Small Cell Lung Cancer Associated with Banking of Frozen Tumor Specimens and Collection of Gene Expression Profile Data | Adult CIRB - Late Phase Emphasis | Completed |
| S1011 | SWOG | A Phase III Surgical Trial to Evaluate the Benefit of a Standard Versus an Extended Pelvic Lymphadenectomy Performed at Time of Radical Cystectomy for Muscle Invasive Urothelial Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071701 | Alliance | Genomically-Guided Treatment Trial in Brain Metastases | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA6194 | ECOG-ACRIN | Phase II Randomized Study of Neoadjuvant Pembrolizumab Alone or in Combination with CMP-001 in Patients with Operable Melanoma: Efficacy and Biomarker Study | Adult CIRB - Late Phase Emphasis | Available to Open |
| CALGB-50303 | CALGB | Phase III Randomized Study of R-CHOP v. Dose-Adjusted EPOCH-R with Molecular Profiling in Untreated De Novo Diffuse Large B-Cell Lymphomas | Adult CIRB - Late Phase Emphasis | Completed |
| S2104 | SWOG | Randomized Phase II Trial of Postoperative Adjuvant Capecitabine and Temozolomide versus Observation in High-Risk Pancreatic Neuroendocrine Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |
| E1Y03 | ECOG | Master Protocol for Pharmacogenetic and Genomic Studies. | Adult CIRB - Late Phase Emphasis | Completed |