CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S1815 | SWOG | A Phase III Randomized Trial of Gemcitabine, Cisplatin, and Nab-Paclitaxel versus Gemcitabine and Cisplatin in Newly Diagnosed, Advanced Biliary Tract Cancers | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-LU003 | NRG | A Biomarker-Driven Protocol for Previously Treated ALK-Positive Non-Squamous NSCLC Patients: The NCI-NRG ALK Protocol | Adult CIRB - Late Phase Emphasis | Available to Open |
| NSABP-B-52 | NSABP | A Randomized Phase III Trial Evaluating Pathologic Complete Response Rates in Patients with Hormone Receptor-Positive; HER2-Positive; Large Operable and Locally Advanced Breast Cancer Treated with Neoadjuvant Therapy of Docetaxel; Carboplatin; Trastuzumab; and Pertuzumab (TCHP) With or Without Estrogen Deprivation | Adult CIRB - Late Phase Emphasis | Completed |
| E3805 | ECOG | CHAARTED: ChemoHormonal Therapy versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA2186 | ECOG-ACRIN | A Randomized Phase II Study of Gemcitabine and Nab-Paclitaxel Compared with 5-Fluorouracil, Leucovorin, and Liposomal Irinotecan in Older Patients with Treatment Naïve Metastatic Pancreatic Cancer (GIANT) | Adult CIRB - Late Phase Emphasis | Available to Open |
| PACCT-1 | ECOG | Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| S9925 | SWOG | Lung Cancer Specimen Repository Protocol Ancillary | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GU010 | NRG | Parallel Phase III Randomized Trials of Genomic-Risk Stratified Unfavorable Intermediate Risk Prostate Cancer: De-Intensification and Intensification Clinical Trial Evaluation (GUIDANCE) | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071102 | Alliance | A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation | Adult CIRB - Late Phase Emphasis | Available to Open |
| CALGB-40101 | CALGB | Cyclophosphamide and Doxorubicin (CA X 4 Cycles) Versus Paclitaxel (4 Cycles) as Adjuvant Therapy for Breast Cancer in Women with 0-3 Positive Axillary Lymph Nodes: A Phase III Randomized Study | Adult CIRB - Late Phase Emphasis | Completed |