CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| 9930 | ETCTN | A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL) | Adult CIRB - Early Phase Emphasis | Available to Open |
| S1512 | SWOG | A Phase II and Pilot Trial of PD-1 Blockade with MK-3475 (Pembrolizumab) in Patients with Resectable or Unresectable Desmoplastic Melanoma (DM) | Adult CIRB - Late Phase Emphasis | Available to Open |
| PED-CITN-03 | Pediatric CITN | Phase 1 Trial of Hu5F9-G4 (Magrolimab) Combined with Dinutuximab in Children and Young Adults with Relapsed and Refractory Neuroblastoma or Relapsed Osteosarcoma | Pediatric CIRB | Available to Open |
| WF-97415 | NCORP-Wake Forest University | Understanding and Predicting Breast Cancer Events after Treatment (UPBEAT) | Cancer Prevention and Control CIRB | Available to Open |
| A092001 | Alliance | Phase 2 Randomized Trial of Neoadjuvant or Palliative Chemotherapy with or Without Immunotherapy for Peritoneal Mesothelioma | Adult CIRB - Late Phase Emphasis | Available to Open |
| E2905 | ECOG | Randomized Phase III Trial Comparing the Frequency of Major Erythroid Response (MER) to Treatment with Lenalidomide (Revlimid) Alone and in Combination with Epoetin Alfa (Procrit) in Subjects with Low- or Intermediate-1 Risk MDS and Symptomatic Anemia | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2212 | SWOG | Shorter Anthracycline-Free Chemo Immunotherapy Adapted to Pathological Response in Early Triple Negative Breast Cancer (SCARLET), A Randomized Phase III Study | Adult CIRB - Late Phase Emphasis | Available to Open |
| 10464 | ETCTN | A Phase 1 Study of Olaparib in Combination with Durvalumab (MEDI4736) and Concurrent Radiation Therapy Following First-Line Chemotherapy in Locally Advanced Unresectable Pancreatic Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| EA1183 | ECOG-ACRIN | FDG PET to Assess Therapeutic Response in Patients with Bone-dominant Metastatic Breast Cancer, FEATURE | Adult CIRB - Late Phase Emphasis | Available to Open |
| PBTC-053 | PBTC | A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma | Pediatric CIRB | Available to Open |