CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| NRG-GY018 | NRG | A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC #776864) in Addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| UMI23-13-01 | CP-CTNet_LAO-University of Michigan | An Early Phase 1 Trial of Omeprazole and Low Dose Aspirin to Identify Colorectal Biomarkers of Preventive Efficacy | Cancer Prevention and Control CIRB | Available to Open |
| 10273 | ETCTN | A Phase 1 Study of M3814 in combination with MEC in Patients with Relapsed or Refractory Acute Myeloid Leukemia | Adult CIRB - Early Phase Emphasis | Available to Open |
| NRG-GY003 | NRG | Phase II Randomized Trial of Nivolumab with or without Ipilimumab in Patients with Persistent or Recurrent Epithelial Ovarian; Primary Peritoneal or Fallopian Tube Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| RTOG-0924 | RTOG | Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| AOST1321 | COG | Phase II Study of Denosumab (IND #127430; NSC# 744010); a RANK Ligand Antibody; for Recurrent or Refractory Osteosarcoma | Pediatric CIRB | Available to Open |
| APEC14B1 | COG | The Project: Everychild Protocol: A Registry; Eligibility Screening; Biology and Outcome Study | Pediatric CIRB | Available to Open |
| CITN-17 | CITN | Phase 1 Study of NT-I7 (rhIL-7-hyFc) for the Treatment of Kaposi Sarcoma in Patients With or Without Infection with HIV | Adult CIRB - Early Phase Emphasis | Available to Open |
| APAL2020SC | COG | Pediatric Acute Leukemia (PedAL) Screening Trial – Developing New Therapies for Relapsed Leukemias | Pediatric CIRB | Available to Open |
| AALL0631 | COG | A Phase III Study of Risk Directed Therapy for Infants with Acute Lymphoblastic Leukemia (ALL): Randomization of Highest Risk Infants to Intensive Chemotherapy FLT3 Inhibition (CEP-701; Lestaurtinib; IND#76431; NSC#617807) | Pediatric CIRB | Available to Open |