CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| E2212 | ECOG | A Randomized; Double-Blinded; Placebo-Controlled Phase II Study of Adjuvant Everolimus Following the Resection of Metastatic Pancreatic Neuroendocrine Tumors to the Liver | Adult CIRB - Early Phase Emphasis | Completed |
| GOG-0277 | GOG | A Phase III Randomized Trial of Gemcitabine (NSC# 613327) Plus Docetaxel (NSC# 628503) Followed by Doxorubicin (NCS# 123127) versus Observation for Uterus-Limited; High Grade Uterine Leiomyosarcoma | Adult CIRB - Late Phase Emphasis | Completed |
| CALGB-90401 | CALGB | A Randomized Double-Blinded Placebo Controlled Phase III Trial Comparing Docetaxel and Prednisone with and without Bevacizumab (IND #7921; NSC #704865) in Men with Hormone Refractory Prostate Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ADVL1221 | COG | A Phase II Study of Cixutumumab (IMC-A12; IND# 100947) in Combination with Temsirolimus (IND# 61010) in Pediatric Patients with Recurrent or Refractory Solid Tumors | Pediatric CIRB | Completed |
| ACOSOG-Z4032 | ACSOG | A Randomized Phase III Study of Sublobar Resection versus Sublobar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC); 3 cm or Smaller | Adult CIRB - Late Phase Emphasis | Completed |
| RTOG-0320 | RTOG | A Phase III Trial Comparing Whole Brain Radiation and Stereotactic Radiosurgery Alone Versus with Temozolomide or Erlotinib in Patients with Non-Small Cell Lung Cancer and 1-3 Brain Metastases | Adult CIRB - Late Phase Emphasis | Completed |
| S0303 | SWOG | A Phase III Trial of Modified FOLFOX6 Versus CAPOX; with Bevacizumab (NSC-704865) or Placebo; as First-Line Therapy in Patients with Previously Untreated Advanced Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| 9914 | ETCTN | A Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors | Adult CIRB - Early Phase Emphasis | Completed |
| ACCL0431 | COG | A Randomized Phase III Study of Sodium Thiosulfate (IND#72877; NSC#45624) for the Prevention of Cisplatin-Induced Ototoxicity in Children: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| S1203 | SWOG | A Randomized Phase III Study of Standard Cytarabine plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) versus IA with Vorinostat (NSC-701852) (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML) | Adult CIRB - Late Phase Emphasis | Completed |