CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| AALL03B1 | COG | Classification of Acute Lymphoblastic Leukemia | Pediatric CIRB | Completed |
| GOG-0249 | GOG | A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed By Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk; Early Stage Endometrial Carcinoma | Adult CIRB - Late Phase Emphasis | Completed |
| AALL07P4 | COG | A Pilot Study of Intravenous EZN-2285 (SC-PEG E. coli L-asparaginase; IND# 100594) or Intravenous Oncaspar in the Treatment of Patients with High-Risk Acute Lymphoblastic Leukemia (ALL): A Limited Institution Pilot Study | Pediatric CIRB | Completed |
| NRG-BN002 | NRG | Phase I Study Of Ipilimumab; Nivolumab; And The Combination In Patients With Newly Diagnosed Glioblastoma | Adult CIRB - Early Phase Emphasis | Completed |
| NSABP-C-08 | NSABP | A Phase III Clinical Trial Comparing Infusional 5-Fluorouracil (5-FU); Leucovorin; and Oxaliplatin (mFOLFOX6) Every Two Weeks with Bevacizumab to the Same Regimen without Bevacizumab for the Treatment of Patients with Resected Stages II and III Carcinoma of the Colon | Adult CIRB - Late Phase Emphasis | Completed |
| E4201 | ECOG | A Randomized Phase III Study of Gemcitabine in Combination with Radiation Therapy Versus Gemcitabine Alone in Patients with Localized; Unresectable Pancreatic Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| ARST0332 | COG | Risk-Based Treatment for Non-Rhabdomyosarcoma Soft Tissue Sarcomas (NRSTS) in Patients Under 30 Years of Age: A Groupwide Phase III Study | Pediatric CIRB | Completed |
| ADVL0525 | COG | A Phase II Study of Pemetrexed in Children with Recurrent Malignancies | Pediatric CIRB | Completed |
| 10608 | ETCTN | A Phase II Trial of Durvalumab with Gemcitabine and Cisplatin as Neoadjuvant Therapy for High-Risk Resectable Intrahepatic Cholangiocarcinoma | Adult CIRB - Early Phase Emphasis | Completed |
| AGCT0521 | COG | Treatment of Recurrent or Resistant Pediatric Malignant Germ Cell Tumors with Paclitaxel; Ifosfamide and Carboplatin: A Groupwide Phase II Study | Pediatric CIRB | Completed |