CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EA5163 | ECOG-ACRIN | INSIGNA: A Randomized, Phase III Study of Firstline Immunotherapy alone or in Combination with Chemotherapy in Induction/Maintenance or Postprogression in Advanced Nonsquamous Non-Small Cell Lung Cancer (NSCLC) with Immunobiomarker SIGNature-driven Analysis | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2205 | SWOG | Ice Compress: Randomized Trial Of Limb Cryocompression Versus Continuous Compression Versus Low Cyclic Compression For The Prevention Of Taxane-Induced Peripheral Neuropathy | Cancer Prevention and Control CIRB | Available to Open |
| 10216 | ETCTN | A Phase I/II Study of AZD9291 (Osimertinib) and CB-839 HCl in Patients with EGFR Mutant Non-Small Cell Lung Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| 9944 | ETCTN | Phase 2 Study of M6620 (VX-970) in Combination with gemcitabine versus gemcitabine alone in Subjects with Platinum-Resistant Recurrent Ovarian or Primary Peritoneal Fallopian Tube Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| ACCL1931 | COG | A Randomized Trial of Levocarnitine Prophylaxis to Prevent Asparaginase-Associated Hepatotoxicity in Adolescents and Young Adults Receiving Acute Lymphoblastic Leukemia Therapy | Pediatric CIRB | Available to Open |
| RTOG-1016 | RTOG | Phase III Trial of Radiotherapy Plus Cetuximab Versus Chemoradiotherapy in HPV-Associated Oropharynx Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| AREN1921 | COG | Treatment of Newly Diagnosed Diffuse Anaplastic Wilms Tumors (DAWT) and Relapsed Favorable Histology Wilms Tumors (FHWT) | Pediatric CIRB | Available to Open |
| ARAR0332 | COG | Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy: A Groupwide Phase III Study | Pediatric CIRB | Available to Open |
| NRG-CC005 | NRG | FORTE (Five or Ten Year Colonoscopy for 1-2 Non-Advanced Adenomatous Polyps) | Cancer Prevention and Control CIRB | Available to Open |
| ADVL1614 | COG | A Phase 1/2 Study of VX15/2503 (IND #136181) in Children, Adolescents, or Young Adults with Recurrent or Relapsed Solid Tumors | Pediatric CIRB | Available to Open |