CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S1203 | SWOG | A Randomized Phase III Study of Standard Cytarabine plus Daunorubicin (7+3) Therapy or Idarubicin with High Dose Cytarabine (IA) versus IA with Vorinostat (NSC-701852) (IA+V) in Younger Patients with Previously Untreated Acute Myeloid Leukemia (AML) | Adult CIRB - Late Phase Emphasis | Completed |
| S1600 | SWOG | A Randomized Phase III Double-Blind Clinical Trial Evaluating the Effect of Immune-Enhancing Nutrition on Radical Cystectomy Outcomes | Cancer Prevention and Control CIRB | Available to Open |
| S0777 | SWOG | A Randomized Phase III Trial of CC-5013 (Lenalidomide; NSC-703813) and Low Dose Dexamethasone (LLD) Versus Bortezomib (PS-341; NSC-681239); Lenalidomide and Low Dose Dexamethasone (BLLD) for Induction; in Patients with Previously Untreated Multiple Myeloma without an Intent for Immediate Autologous Stem Cell Transplant | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1500 | SWOG | A Randomized; Phase II Efficacy Assessment of Multiple MET Kinase Inhibitors (Cabozantinib [NSC #761968]; Crizotinib [NSC #749005]; Savolitinib [NSC #785348]; and Sunitinib [NSC #736511]) in Metastatic Papillary Renal Carcinoma (PAPMET) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2104 | SWOG | Randomized Phase II Trial of Postoperative Adjuvant Capecitabine and Temozolomide versus Observation in High-Risk Pancreatic Neuroendocrine Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |
| S2010 | SWOG | A Randomized Phase III Trial Comparing Active Symptom Monitoring Plus Patient Education Versus Patient Education Alone To Improve Persistence With Endocrine Therapy In Young Women With Stage I-III Breast Cancer (Aspen) | Cancer Prevention and Control CIRB | Available to Open |
| S1823 | SWOG | A Prospective Observational Cohort Study To Assess miRNA 371 For Outcome Prediction in Patients With Newly Diagnosed Germ Cell Tumors | Cancer Prevention and Control CIRB | Available to Open |
| S0200 | SWOG | A Phase III Randomized Study of Pegylated Liposomal Doxorubicin Plus Carboplatin Versus Carboplatin in Platinum-Sensitive Patients with Recurrent Epithelial Ovarian or Peritoneal Carcinoma After Failure of Initial Platinum-Based Chemotherapy | Adult CIRB - Late Phase Emphasis | Completed |
| S1400 | SWOG | A Biomarker-Driven Master Protocol for Previously Treated Squamous Cell Lung Cancer (Lung-Map) | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1900C | SWOG | A Phase II Study of Talazoparib plus Avelumab in Patients with Stage IV or Recurrent Non-Squamous Non-Small Cell Lung Cancer Bearing Pathogenic STK11 Genomic Alterations (LungMAP Sub-Study) | Adult CIRB - Late Phase Emphasis | Available to Open |