CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| A011106 | Alliance | ALTernate approaches for clinical stage II or III Estrogen Receptor positive breast cancer NeoAdjuvant TrEatment (ALTERNATE) in postmenopausal women: A Phase III Study | Adult CIRB - Late Phase Emphasis | Available to Open |
| A091304 | Alliance | A Phase I /Randomized Phase II Study of MLN0128 (TAK-228) vs. Pazopanib In Patients With Locally Advanced/Unresectable And/Or Metastatic Sarcoma | Adult CIRB - Early Phase Emphasis | Completed |
| A092104 | Alliance | A Randomized Phase 2/3 Study of Olaparib plus Temozolomide versus Investigator's Choice for the Treatment of Patients with Advanced Uterine Leiomyosarcoma after Progression on Prior Chemotherapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| A071102 | Alliance | A Phase II/III Randomized Trial Of Veliparib Or Placebo In Combination With Adjuvant Temozolomide In Newly Diagnosed Glioblastoma With MGMT Promoter Hypermethylation | Adult CIRB - Late Phase Emphasis | Available to Open |
| A211901 | Alliance | Reaching Rural Cancer Survivors Who Smoke Using Text-Based Cessation Interventions | Cancer Prevention and Control CIRB | Available to Open |
| A231701CD | Alliance | Increasing Socioeconomically Disadvantaged Patients’ Engagement in Breast Cancer Surgery Decision Making Through a Shared Decision Making Intervention | Cancer Prevention and Control CIRB | Available to Open |
| A221602 | Alliance | Olanzapine with or without fosaprepitant for the prevention of chemotherapy induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC): A Phase III Randomized, Double Blind, Placebo-Controlled Trial | Cancer Prevention and Control CIRB | Available to Open |
| A221504 | Alliance | A Randomized, Double-Blind, Placebo-Controlled Pilot Study of an Oral, Selective Peripheral Opioid Receptor Antagonist in Advanced Non-Small Cell Lung Cancer | Cancer Prevention and Control CIRB | Available to Open |
| A051901 | Alliance | Phase I Trial of Methotrexate, Rituximab, Lenalidomide, and Nivolumab (NIVO-MR2) Induction Followed by Lenalidomide and Nivolumab Maintenance in Primary CNS Lymphoma | Adult CIRB - Early Phase Emphasis | Available to Open |
| A031102 | Alliance | A Randomized Phase III Trial Comparing Conventional-Dose Chemotherapy Using Paclitaxel; Ifosfamide; and Cisplatin (TIP) with High-Dose Chemotherapy Using Mobilizing Paclitaxel Plus Ifosfamide followed by High-Dose Carboplatin and Etoposide (TI-CE) as First Salvage Treatment in Relapsed or Refractory Germ Cell Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |