CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| ACOSOG-Z4032 | ACSOG | A Randomized Phase III Study of Sublobar Resection versus Sublobar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC); 3 cm or Smaller | Adult CIRB - Late Phase Emphasis | Completed |
| A022004 | Alliance | Randomized Trial of Consolidation Targeted Adjuvant Therapy with Encorafenib and Cetuximab versus Usual Care for Patients with Stage II/III BRAF V600E Colon Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA2183 | ECOG-ACRIN | A Phase III Study of Consolidative Radiotherapy in Patients with Oligometastatic HER2 Negative Esophageal and Gastric Adenocarcinoma (EGA) | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-LU007 | NRG | RAndomized Phase II/III Trial Of Consolidation Radiation + Immunotherapy for ES-SCLC: RAPTOR trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| ANZGOG-0902-GOG-0274 | GOG | A Phase III Trial of Adjuvant Chemotherapy Following Chemoradiation as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174) | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-0320 | RTOG | A Phase III Trial Comparing Whole Brain Radiation and Stereotactic Radiosurgery Alone Versus with Temozolomide or Erlotinib in Patients with Non-Small Cell Lung Cancer and 1-3 Brain Metastases | Adult CIRB - Late Phase Emphasis | Completed |
| S0303 | SWOG | A Phase III Trial of Modified FOLFOX6 Versus CAPOX; with Bevacizumab (NSC-704865) or Placebo; as First-Line Therapy in Patients with Previously Untreated Advanced Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GY024 | NRG | Groningen International Study on Sentinel Nodes in Vulvar Cancer (GROINSS-V) III: A Prospective Phase II Treatment Trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA8143 | ECOG-ACRIN | A Phase 3 RandOmized Study Comparing PERioperative Nivolumab vs. Observation in Patients with Renal Cell Carcinoma Undergoing Nephrectomy (PROSPER RCC) | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI006 | NRG | Phase III Randomized Trial of Proton Beam Therapy (PBT) versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |