CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| EA1181 | ECOG-ACRIN | (CompassHER2-pCR): Preoperative THP and postoperative HP in patients who achieve a pathologic complete response | Adult CIRB - Late Phase Emphasis | Available to Open |
| A092105 | Alliance | Randomized Phase 2 Study of Nivolumab and Ipilimumab with or without Cabozantinib in Patients with Advanced Nasopharyngeal Carcinoma that have Progressed after Platinum Treatment and Immunotherapy | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GY032 | NRG | A Phase II Study of Tailored Adjuvant Therapy in Pole-Mutated and p53-Wildtype/NSMP Early-Stage Endometrial Cancer (RAINBO BLUE & TAPER) | Adult CIRB - Late Phase Emphasis | Available to Open |
| GOG-0263 | GOG | Randomized Phase III Clinical Trial of Adjuvant Radiation Versus Chemoradiation in Intermediate Risk; Stage I/IIA Cervical Cancer Treated with Initial Radical Hysterectomy and Pelvic Lymphadenectomy | Adult CIRB - Late Phase Emphasis | Available to Open |
| 9149 | ETCTN | Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors | Adult CIRB - Late Phase Emphasis | Available to Open |
| E1609 | ECOG | A Phase III Randomized Study of Adjuvant Ipilimumab Anti-CTLA4 Therapy Versus High-Dose Interferon a-2b for Resected High-Risk Melanoma<br> | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA8212 | ECOG-ACRIN | A Randomized Phase III Trial of Intravesical BCG veRsus Intravesical Docetaxel and GEmcitabine Treatment in BCG Naïve High Grade Non-Muscle Invasive Bladder Cancer (BRIDGE) | Adult CIRB - Late Phase Emphasis | Available to Open |
| EA1211 | ECOG-ACRIN | Interim FDG-PET/CT for PreDIcting REsponse of HER2+ Breast Cancer to Neoadjuvant Therapy: DIRECT trial | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU008 | NRG | Randomized Phase III Trial Incorporating Abiraterone Acetate with Prednisone and Apalutamide and Advanced Imaging into Salvage Treatment for Patients with Node-Positive Prostate Cancer after Radical Prostatectomy | Adult CIRB - Late Phase Emphasis | Available to Open |
| E3805 | ECOG | CHAARTED: ChemoHormonal Therapy versus Androgen Ablation Randomized Trial for Extensive Disease in Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |