CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| AAML1421 | COG | A Phase 1/2 Study of CPX-351 (NSC# 775341; IND #129443) Alone Followed by Fludarabine; Cytarabine; and G-CSF (FLAG) for Children with Relapsed Acute Myeloid Leukemia (AML) | Pediatric CIRB | Available to Open |
| ADVL1823 | COG | Larotrectinib (LOXO-101, NSC# 788607, IND# 141824) for Previously Untreated TRK Fusion Pediatric Solid Tumors and TRK Fusion Relapsed Pediatric Acute Leukemias | Pediatric CIRB | Available to Open |
| AALL0433 | COG | Intensive Treatment for Intermediate-Risk Relapse of Childhood B-Precursor Acute Lymphoblastic Leukemia (ALL): A Randomized Trial of Vincristine Strategies. A Groupwide Phase III Study | Pediatric CIRB | Completed |
| ACNS0221 | COG | A Phase II Study of Conformal Radiotherapy In Patients with Low-Grade Gliomas | Pediatric CIRB | Completed |
| AEPI07N1 | COG | Genetic Susceptibility Factors in the Etiology of Neuroblastoma also known as Neuroblastoma Epidemiology in North America (NENA): A Groupwide Non-Therapeutic Study | Pediatric CIRB | Completed |
| UAZ21-06-01 | CP-CTNet_CLO-University of Arizona | Phase II Randomized, Double Blind, Placebo-Controlled Trial of the Broccoli Seed and Sprout Extract (BSSE), Avmacol ES, to Evaluate Sustained Detoxification of Tobacco Carcinogens in Heavy Smokers | Cancer Prevention and Control CIRB | Available to Open |
| EAQ162CD | ECOG-ACRIN | Longitudinal Assessment of Financial Burden in Patients with Colon or Rectal Cancer Treated with Curative Intent | Cancer Prevention and Control CIRB | Available to Open |
| UAZ2017-09-02 | CP-CTNet_CLO-University of Arizona | Clinical Study of Avmacol® for Detoxification of Tobacco Carcinogens in Heavy Smokers | Cancer Prevention and Control CIRB | Completed |
| EA9131 | ECOG-ACRIN | A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL) | Cancer Prevention and Control CIRB | Available to Open |
| NRG-CC009 | NRG | Phase III Trial of Stereotactic Radiosurgery (SRS) versus Hippocampal-Avoidant Whole Brain Radiotherapy (HA-WBRT) for 10 or fewer Brain Metastases from Small Cell Lung Cancer | Cancer Prevention and Control CIRB | Available to Open |