Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NCIC-BR.19||NCIC CTG||A Phase III Prospective Randomized; Double-Blind; Placebo-Controlled Trial of the Epidermal Growth Factor Receptor Antagonist; ZD1839 (IRESSA) in Completely Resected Primary Stage IB; II and IIIA Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|CALGB-90106||CALGB||A Randomized Phase III Study of Paclitaxel; Ifosfamide and Cisplatin Versus Vinblastine; Ifosfamide and Cisplatin as Second-Line Therapy for Patients with Relapsed/Resistant Germ Cell Tumors||Adult CIRB - Late Phase Emphasis||Completed|
|S0200||SWOG||A Phase III Randomized Study of Pegylated Liposomal Doxorubicin Plus Carboplatin Versus Carboplatin in Platinum-Sensitive Patients with Recurrent Epithelial Ovarian or Peritoneal Carcinoma After Failure of Initial Platinum-Based Chemotherapy||Adult CIRB - Late Phase Emphasis||Completed|
|ARET0331||COG||Trial of Systemic Neoadjuvant Chemotherapy for Group B Intraocular Retinoblastoma: A Phase III Limited Institution Study||Pediatric CIRB||Completed|
|E4599||ECOG||Randomized Phase II/III Trial of Paclitaxel plus Carboplatin With or Without Bevacizumab (NSC #704865) in Patients with Advanced Nonsquamous NSCLC||Adult CIRB - Late Phase Emphasis||Completed|
|ACNS1021||COG||A Phase II Study of Sunitinib (NSC# 736511; IND# 74019) in Recurrent; Refractory or Progressive High Grade Glioma and Ependymoma Tumors in Pediatric and Young Adult Patients||Pediatric CIRB||Completed|
|NSABP-B-34||NSABP||A Clinical Trial Comparing Adjuvant Clodronate Therapy vs. Placebo in Early-Stage Breast Cancer Patients Receiving Systemic Chemotherapy and/or Hormonal Therapy or No Therapy||Adult CIRB - Late Phase Emphasis||Completed|
|RTOG-0825||RTOG||Phase III Double-Blind Placebo-Controlled Trial of Conventional Concurrent Chemoradiation and Adjuvant Temozolomide plus Bevacizumab versus Conventional Concurrent Chemoradiation and Adjuvant Temozolomide in Patients with Newly Diagnosed Glioblastoma||Adult CIRB - Late Phase Emphasis||Completed|
|S0427||SWOG||A Phase III Trial of Standard Fractionation Radiation and Concurrent Single Agent Cisplatin; with and without Docetaxel; Cisplatin; and 5-FluorouracilInduction Chemotherapy; in Patients with Advanced Oropharyngeal Squamous Cell Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|N0949||NCCTG||Randomized Phase III Trial of mFOLFOX7 or XELOX Plus Bevacizumab Versus 5-Fluorouracil/Leucovorin or Capecitabine Plus Bevacizumab as First-line Treatment in Elderly Patients with Metastatic Colorectal Cancer||Adult CIRB - Late Phase Emphasis||Completed|