Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|E1302||ECOG||Phase III Randomized; Placebo-Controlled Trial of Docetaxel Versus Docetaxel Plus ZD1839 (Iressa; Gefitinib) in Performance Status 2 or Previously Treated Patients with Recurrent or Metastatic Head and Neck Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|NSABP-B-36||NSABP||A Clinical Trial of Adjuvant Therapy Comparing Six Cycles of 5-Fluorouracil; Epirubicin and Cyclophosphamide (FEC) to Four Cycles of Adriamycin and Cyclophosphamide (AC) in Patients with Node-Negative Breast Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|ACNS1021||COG||A Phase II Study of Sunitinib (NSC# 736511; IND# 74019) in Recurrent; Refractory or Progressive High Grade Glioma and Ependymoma Tumors in Pediatric and Young Adult Patients||Pediatric CIRB||Completed|
|NRG-GI001||NRG||Randomized Phase III Study of Focal Radiation Therapy for Unresectable; Localized Intrahepatic Cholangiocarcinoma||Adult CIRB - Late Phase Emphasis||Completed|
|S0347||SWOG||A Randomized Study of Weekly Vinorelbine (Navelbine) Alone or in Combination with Trastuzumab (Herceptin) (NSC-688097) for Patients with HER-2-Positive Metastatic Breast Cancer Whose Tumors Have Progressed After Taxane + Trastuzumab Combination Therapy - Phase III||Adult CIRB - Late Phase Emphasis||Completed|
|NSABP-R-04||NSABP||A Clinical Trial Comparing Preoperative Radiation Therapy and Capecitabine with or without Oxaliplatin with Preoperative Radiation Therapy and Continuous Intravenous Infusion of 5-Fluorouracil with or without Oxaliplatin in the Treatment of Patients with Operable Carcinoma of the Rectum||Adult CIRB - Late Phase Emphasis||Completed|
|E1Y03||ECOG||Master Protocol for Pharmacogenetic and Genomic Studies.||Adult CIRB - Late Phase Emphasis||Completed|
|ACCL0631||COG||Impact of Obesity on the Pharmacokinetics of Anticancer Therapy in Children with High Risk Acute Lymphoblastic Leukemia (ALL): A Group-wide Non-Therapeutic Study||Pediatric CIRB||Completed|
|ADVL1315||COG||A Phase 1 Study of the VEGF Receptor Tyrosine Kinase Inhibitor Axitinib (INLYTA; 123101) in Children with Recurrent or Refractory Solid Tumors||Pediatric CIRB||Completed|
|CALGB-80303||CALGB||A Randomized Phase III Trial of Gemcitabine Plus Bevacizumab (NSC #704865 IND# 7921) Versus Gemcitabine Plus Placebo in Patients with Advanced Pancreatic Cancer||Adult CIRB - Late Phase Emphasis||Completed|