CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 31 - 40 of 649
Study Numbersort descending Lead Group Study Title CIRB Study Status
10107 ETCTN Phase 1 Safety Run-In and Phase 2 Randomized Clinical Trial of Anetumab Ravtansine and MK-3475 (Pembrolizumab) Compared to MK-3475 (Pembrolizumab) Alone for Mesothelin-Positive Malignant Pleural Mesothelioma Adult CIRB - Early Phase Emphasis Available to Open
10126 ETCTN A Pilot Phase I Study of Atezolizumab (MPDL3280A) in Combination with Immunogenic Chemotherapy (Gemcitabine-Oxaliplatin) and Rituximab for Transformed Diffuse Large B-Cell Lymphoma Adult CIRB - Early Phase Emphasis Available to Open
10129 ETCTN A Phase 2 Study of the PARP Inhibitor Olaparib (AZD2281) in IDH1 and IDH2 mutant Advanced Solid Tumors Adult CIRB - Early Phase Emphasis Available to Open
10130 ETCTN A phase I study of single agent tazemetostat in subjects with advanced solid tumors and B-cell lymphomas with hepatic dysfunction Adult CIRB - Early Phase Emphasis Available to Open
10131 ETCTN A Phase 1 Study of AZD8186 in Combination with Docetaxel in patients with PTEN mutated or PIK3CB mutated advanced solid tumors, potentially amenable to docetaxel Adult CIRB - Early Phase Emphasis Available to Open
10132 ETCTN A Phase I Study of the Wee 1 kinase (Wee 1) inhibitor AZD1775 in combination with Radiotherapy and Cisplatin in Cervical, Upper Vaginal and Uterine Cancers Adult CIRB - Early Phase Emphasis Available to Open
10136 ETCTN A Phase 2 Study Of AZD1775, A WEE1 Inhibitor, In Patients With CCNE1 Amplification Adult CIRB - Early Phase Emphasis Available to Open
10139 ETCTN A Randomized Phase 2 Study of Atezolizumab in Combination with Cobimetinib versus Atezolizumab Monotherapy in Participants with Unresectable Cholangiocarcinoma Adult CIRB - Early Phase Emphasis Available to Open
10144 ETCTN A Phase II Study of Olaparib (AZD2281) in Patients with Metastatic/Advanced Urothelial Carcinoma with DNA-Repair Defects Adult CIRB - Early Phase Emphasis Available to Open
10145 ETCTN Phase IB Combination Study Of Copanlisib And Nivolumab In Advanced Solid Tumors And Lymphomas Adult CIRB - Early Phase Emphasis Available to Open
Displaying 31 - 40 of 649