Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|ADVL1615||COG||A Phase 1 Study of Pevonedistat (MLN4924, IND # 136078), A NEDD8 Activating Enzyme (NAE) Inhibitor, in Combination with Temozolomide and Irinotecan in Pediatric Patients with Recurrent or Refractory Solid Tumors||Pediatric CIRB||Available to Open|
|NRG-BN002||NRG||Phase I Study Of Ipilimumab; Nivolumab; And The Combination In Patients With Newly Diagnosed Glioblastoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|ANBL0532||COG||Phase III Randomized Trial of Single vs. Tandem Myeloablative Consolidation Therapy for High-Risk Neuroblastoma: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|AGCT1531||COG||A Phase 3 Study of Active Surveillance for Low risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors||Pediatric CIRB||Available to Open|
|10010||ETCTN||A Phase 2 Study of Atezolizumab (MPDL3280A) in Combination with Bevacizumab in Patients with Recurrent; Persistent or Metastatic Cervical Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|A221701||Alliance||Phase III Placebo-Controlled Trial to Evaluate Dexamethasone Use for Everolimus-Induced Oral Stomatitis: Prevention Versus Early Treatment Approaches||Cancer Prevention and Control CIRB||Available to Open|
|ACNS1123||COG||Phase 2 Trial of Response-Based Radiation Therapy for Patients with Localized Central Nervous System Germ Cell Tumors (CNS GCT): A Groupwide Phase II Study||Pediatric CIRB||Available to Open|
|9149||ETCTN||Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors||Adult CIRB - Late Phase Emphasis||Available to Open|
|ABTC-1701||ABTC||Pilot Surgical PK Study of BGB324 in Recurrent Glioblastoma Patients||Adult CIRB - Early Phase Emphasis||Available to Open|
|AALL1331||COG||Risk-Stratified Randomized Phase III Testing of Blinatumomab (IND# 117467; NSC#765986) in First Relapse of Childhood B-Lymphoblastic Leukemia (B-ALL): A Groupwide Phase III Study||Pediatric CIRB||Available to Open|