CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 11 - 20 of 666
Study Number Lead Group Study Title CIRB Study Status
GOG-0277 GOG A Phase III Randomized Trial of Gemcitabine (NSC# 613327) Plus Docetaxel (NSC# 628503) Followed by Doxorubicin (NCS# 123127) versus Observation for Uterus-Limited; High Grade Uterine Leiomyosarcoma Adult CIRB - Late Phase Emphasis Available to Open
CALGB-40601 CALGB Randomized Phase III Trial of Paclitaxel + Trastuzumab + Lapatinib Versus Paclitaxel + Trastuzumab as Neoadjuvant Treatment of HER2-Positive Primary Breast Cancer Adult CIRB - Late Phase Emphasis Available to Open
S1404 SWOG A Phase III Randomized Trial Comparing Physician/Patient Choice of Either High Dose Interferon or Ipilimumab to MK-3475 (Pembrolizumab) in Patients with High Risk Resected Melanoma Adult CIRB - Late Phase Emphasis Available to Open
NRG-GY012 NRG A Randomized Phase II Study Comparing Single-Agent Olaparib, Single Agent Cediranib, and the Combination of Cediranib/Olaparib in Women with Recurrent, Persistent or Metastatic Endometrial Cancer Adult CIRB - Late Phase Emphasis Available to Open
ACOSOG-Z4099 ACSOG A Randomized Phase III Study of Sublobar Resection (+/- Brachytherapy) versus Stereotactic Body Radiation Therapy in High Risk Patients with Stage I Non-Small Cell Lung Cancer (NSCLC)<br><br> Adult CIRB - Late Phase Emphasis Completed
RTOG-1010 RTOG A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma Adult CIRB - Late Phase Emphasis Available to Open
NRG-GY007 NRG A Phase I/II Study of Ruxolitinib with Front-Line Neoadjuvant and Post-Surgical Therapy in Patients with Advanced Epithelial Ovarian; Fallopian Tube; or Primary Peritoneal Cancer Adult CIRB - Late Phase Emphasis Available to Open
NRG-BN003 NRG Phase III Trial of Observation Versus Irradiation for a Gross Totally Resected Grade II Meningioma Adult CIRB - Late Phase Emphasis Available to Open
E2810 ECOG Randomized; Double-Blind Phase III Study of Pazopanib vs. Placebo in Patients with Metastatic Renal Cell Carcinoma Who Have No Evidence of Disease Following Metastatectomy Adult CIRB - Late Phase Emphasis Available to Open
GOG-0249 GOG A Phase III Trial of Pelvic Radiation Therapy Versus Vaginal Cuff Brachytherapy Followed By Paclitaxel/Carboplatin Chemotherapy in Patients with High Risk; Early Stage Endometrial Carcinoma Adult CIRB - Late Phase Emphasis Available to Open
Displaying 11 - 20 of 666