Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|PACCT-1||ECOG||Program for the Assessment of Clinical Cancer Tests (PACCT-1): Trial Assigning Individualized Options for Treatment: The TAILORx Trial||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0214||RTOG||A Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|NRG-GI004||NRG||Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with or without Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients with Deficient DNA Mismatch Repair (dMMR) Metastatic Colorectal Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-30102||CALGB||Phase III Comparison of Catheter Based Therapy of Pleural Effusions in Cancer Patients (Optimal Pleural Effusion Control; OPEC||Adult CIRB - Late Phase Emphasis||Completed|
|A031702||Alliance||Phase II Study of Cabozantinib in Combination with Nivolumab and Ipilimumab in Rare Genitourinary Tumors||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0307||SWOG||Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0920||RTOG||A Phase III Study of Postoperative Radiation Therapy (IMRT) +/- Cetuximab for Locally-Advanced Resected Head and Neck Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|E4A08||ECOG||A Randomized Phase III Trial of Melphalan and Dexamethasone (MDex) versus Bortezomib; Melphalan; and Dexamethasone (BMDex) for Untreated Patients with Systemic Light-chain (AL) Amyloidosis Ineligible for Autologous Stem-cell Transplantation||Adult CIRB - Late Phase Emphasis||Completed|
|EA9152||ECOG-ACRIN||A Phase Ib/II Study of Venetoclax (ABT-199) in Combination with Liposomal Vincristine in Patients with Relapsed or Refractory T-cell or B-cell Acute Lymphoblastic Leukemia||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-80702||CALGB||A Phase III Trial of 6 Versus 12 Treatments of Adjuvant FOLFOX Plus Celecoxib or Placebo for Patients with Resected Stage III Colon Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|