Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|10219||ETCTN||Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma||Adult CIRB - Early Phase Emphasis||Available to Open|
|9914||ETCTN||A Phase I Study of a Combination of MM-398 and Veliparib in Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|AALL1231||COG||A Phase III Randomized Trial Investigating Bortezomib (NSC# 681239; IND# 58443) on a Modified Augmented BFM (ABFM) Backbone in Newly Diagnosed T- Lymphoblastic Leukemia (T-ALL) and T- Lymphoblastic Lymphoma (T-LLy): A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|N1048||NCCTG||A Phase II/III Trial of Neoadjuvant FOLFOX; with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision||Adult CIRB - Late Phase Emphasis||Available to Open|
|A031801||Alliance||A Phase II Randomized Trial of Radium-223 Dichloride and Cabozantinib in Patients with Advanced Renal Cell Carcinoma with Bone Metastasis (RADICAL)||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-CC006||NRG||A Survey Study to Evaluate Physician Attitudes and Perceptions Regarding a Non-Surgical Approach to Breast Cancer Treatment||Cancer Prevention and Control CIRB||Available to Open|
|AHOD1331||COG||A Randomized Phase III Study of Brentuximab Vedotin (SGN-35; IND #117117) for Newly Diagnosed High-Risk Classical Hodgkin Lymphoma (cHL) in Children and Adolescents: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|SCUSF-0901||COG||SCUSF 0901 [ACCL0922] A Phase II Placebo-Controlled Trial of Modafinil to Improve Neurocognitive Deficits in Children Treated for a Primary Brain Tumor||Pediatric CIRB||Available to Open|
|10129||ETCTN||A Phase 2 Study of the PARP Inhibitor Olaparib (AZD2281) in IDH1 and IDH2 mutant Advanced Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|AREN1721||COG||A Randomized Phase 2 Trial of Axitinib/Nivolumab Combination Therapy vs. Single Agent Axitinib or Nivolumab for the Treatment of TFE/Translocation Renal Cell Carcinoma (tRCC) Across All Age Groups||Pediatric CIRB||Available to Open|