Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|9930||ETCTN||A Phase I Trial of MEDI-570 in Patients with Relapsed/Refractory Peripheral T-Cell Lymphoma (PTCL) Follicular Variant and Angioimmunoblastic T-Cell Lymphoma (AITL)||Adult CIRB - Early Phase Emphasis||Available to Open|
|MDA2014-04-01||CLO-MD Anderson||Alternative Dosing of Exemestane in Postmenopausal Women with Stage 0-II ER-Positive Breast Cancer: a Randomized Presurgical Trial||Cancer Prevention and Control CIRB||Available to Open|
|10066||ETCTN||A Phase 1 / 2 Study of Olaparib in Combination with Ramucirumab in Metastatic Gastric and Gastroesophageal Junction Adenocarcinoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|7977||ETCTN||A Phase I Dose-Escalation Study of Oral ABT-888 (NSC #737664) Plus Intravenous Irinotecan (CPT-11, NSC#616348) Administered in Patients with Advanced Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|10335||ETCTN||A Phase 1 Study of Lenalidomide in Combination with EPOCH Chemotherapy for HTLV-Associated Adult T-Cell Leukemia-Lymphoma (ATLL)||Adult CIRB - Early Phase Emphasis||Available to Open|
|10186||ETCTN||A Phase I/II Study of Nivolumab plus or minus Ipilimumab in Combination with Multi-fraction Stereotactic Radiosurgery for Recurrent High-grade Radiation-relapsed Meningioma||Adult CIRB - Early Phase Emphasis||Available to Open|
|A021502||Alliance||Randomized Trial of FOLFOX Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability (ATOMIC*)||Adult CIRB - Late Phase Emphasis||Available to Open|
|9844||ETCTN||A Phase 1 Study Evaluating Safety; Tolerability; and Preliminary Antitumor Activity of Entinostat and Nivolumab with or without Ipilimumab in Advanced Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|AALL08B1||COG||Classification of Newly Diagnosed Acute Lymphoblastic Leukemia (ALL)||Pediatric CIRB||Available to Open|
|AAML0631||COG||Risk Adapted Treatment of Newly Diagnosed Childhood Acute Promyelocytic Leukemia (APL) Using Arsenic Trioxide (Trisenox IND# 103; 331) during Consolidation: A Phase III Study Limited to COG institutions in the United States & Canada||Pediatric CIRB||Available to Open|