Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|EA1183||ECOG-ACRIN||FDG PET to Assess Therapeutic Response in Patients with Bone-dominant Metastatic Breast Cancer, FEATURE||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0819||SWOG||A Randomized; Phase III Study Comparing Carboplatin/Paclitaxel or Carboplatin/Paclitaxel/Bevacizumab with or without Concurrent Cetuximab in Patients with Advanced Non-Small Cell Lung Cancer (NSCLC)||Adult CIRB - Late Phase Emphasis||Available to Open|
|E2805||ECOG||ASSURE: Adjuvant Sorafenib or Sunitinib for Unfavorable Renal Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|A041701||Alliance||A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|NCIC-BR.19||NCIC CTG||A Phase III Prospective Randomized; Double-Blind; Placebo-Controlled Trial of the Epidermal Growth Factor Receptor Antagonist; ZD1839 (IRESSA) in Completely Resected Primary Stage IB; II and IIIA Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|NRG-HN001||RTOG||Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0205||SWOG||A Phase III Randomized Open-Label Study Comparing Gemcitabine Plus Cetuximab (IMC-C225) Versus Gemcitabine as First-Line Therapy of Patients with Advanced Pancreas Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|EA2187||ECOG-ACRIN||A Phase 2 Study of Pevonedistat in Combination with Carboplatin and Paclitaxel in Advanced Intrahepatic Cholangiocarcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-GY011||NRG||A Randomized Surgical Window Pilot Investigation of the Relationship of Short Term Medroxyprogesterone Acetate (NSC #26386) Compared to Medroxyprogesterone Acetate Plus Entinostat (NSC #706995) on the Morphologic, Biochemical, and Molecular Changes in Primary Endometrioid Adenocarcinoma of the Uterine Corpus||Adult CIRB - Late Phase Emphasis||Available to Open|
|E2108||ECOG||A Randomized Phase III Trial of the Value of Early Local Therapy for the Intact Primary Tumor in Patients with Metastatic Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|