Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|E1208||ECOG||A Phase III Randomized; Double-Blind Trial of Chemoembolization with or without Sorafenib in Unresectable Hepatocellular Carcinoma (HCC) in Patients with and without Vascular Invasion||Adult CIRB - Late Phase Emphasis||Available to Open|
|PBTC-051||PBTC||Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma||Pediatric CIRB||Available to Open|
|10170||ETCTN||A Phase 2 Study of AZD1775 in SETD2-Deficient Advanced Solid Tumor Malignancies||Adult CIRB - Early Phase Emphasis||Available to Open|
|NWU2015-06-01||CLO-Northwestern University||Evaluating Intermittent Dosing of Aspirin for Colorectal Cancer Chemoprevention||Cancer Prevention and Control CIRB||Available to Open|
|S1826||SWOG||A Phase III, Randomized Study of Nivolumab (Opdivo) plus AVD or Brentuximab Vedotin (Adcetris) plus AVD in Patient (Age >/= 12 Year) with Newly Diagnosed Advanced Stage Classical Hodgkin Lymphoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|10388||ETCTN||A Phase I Trial of Triapine and Lutetium Lu 177 Dotatate in Combination for Well-Differentiated Somatostatin Receptor-Positive Gastroenteropancreatic Neuroendocrine Tumors (GEP-NETs)||Adult CIRB - Early Phase Emphasis||Available to Open|
|ECOG-EA9131||ECOG-ACRIN||A Simplified Patient Care Strategy to Decrease Early Deaths in Acute Promyelocytic Leukemia (APL)||Cancer Prevention and Control CIRB||Available to Open|
|AALL15P1||COG||A Groupwide Pilot Study to Test the Tolerability and Biologic Activity of the Addition of Azacitidine (IND#TBD; NSC# 102816) to Chemotherapy in Infants with Acute Lymphoblastic Leukemia (ALL) and KMT2A Gene Rearrangement||Pediatric CIRB||Available to Open|
|ACNS0821||COG||Temozolomide with Irinotecan versus Temozolomide; Irinotecan plus Bevacizumab (NSC# 704865; BB-IND# 7921) for Recurrent/Refractory Medulloblastoma/CNS PNET of Childhood; A COG Randomized Phase II Screening Trial: A Groupwide Phase II Study||Pediatric CIRB||Available to Open|
|ANZGOG-0902-GOG-0274||GOG||A Phase III Trial of Adjuvant Chemotherapy Following Chemoradiation as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174)||Adult CIRB - Late Phase Emphasis||Available to Open|