Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|ARAR0332||COG||Treatment of Adrenocortical Tumors with Surgery plus Lymph Node Dissection and Multiagent Chemotherapy: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|9881||ETCTN||A Phase 2 Study of Cediranib in Combination with Olaparib in Advanced Solid Tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|ACCL0933||COG||A Randomized Open-Label Trial of Caspofungin versus Fluconazole to Prevent Invasive Fungal Infections in Children Undergoing Chemotherapy for Acute Myeloid Leukemia (AML): A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|10216||ETCTN||A Phase I/II Study of AZD9291 (Osimertinib) and CB-839 HCl in Patients with EGFR Mutant Non-Small Cell Lung Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|A031201||Alliance||Phase III Trial of Enzalutamide (NSC # 766085) Versus Enzalutamide; Abiraterone and Prednisone for Castration Resistant Metastatic Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|AALL0932||COG||Treatment of Patients with Newly Diagnosed Standard Risk B-Lymphoblastic Leukemia (B-ALL) or Localized B-lineage Lymphoblastic Lymphoma (B-LLy)||Pediatric CIRB||Available to Open|
|10131||ETCTN||A Phase 1 Study of AZD8186 in Combination with Docetaxel in patients with PTEN mutated or PIK3CB mutated advanced solid tumors, potentially amenable to docetaxel||Adult CIRB - Early Phase Emphasis||Available to Open|
|NRG-GY016||NRG||A Phase II Study of MK-3475 (Pembrolizumab) (NSC #776864) + Epacadostat (NSC #766086) in Recurrent Clear Cell Carcinoma of the Ovary||Adult CIRB - Late Phase Emphasis||Available to Open|
|ALTE11C2||COG||Health Effects after Anthracycline and Radiation Therapy (HEART): Dexrazoxane and Prevention of Anthracycline-related Cardiomyopathy: A Limited Institution Non-Therapeutic Study||Pediatric CIRB||Available to Open|
|RTOG-1308||RTOG||Phase III Randomized Trial Comparing Overall Survival After Photon Versus Proton Chemoradiotherapy For Inoperable Stage II-IIIB NSCLC||Adult CIRB - Late Phase Emphasis||Available to Open|