Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|A021302||Alliance||Impact of Early FDG-PET Directed Intervention on Preoperative Therapy for Locally Advanced Gastric Cancer: A Random Assignment Phase II Study||Adult CIRB - Early Phase Emphasis||Completed|
|A011502||Alliance||A Randomized Phase III Double-Blinded Placebo Controlled Trial of Aspirin as Adjuvant Therapy for Node Positive HER2 Negative Breast Cancer: The ABC Trial||Adult CIRB - Late Phase Emphasis||Available to Open|
|A011401||Alliance||Randomized Phase III Trial Evaluating the Role of Weight Loss in Adjuvant Treatment of Overweight and Obese Women with Early Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|A011203||Alliance||A Randomized Phase II Trial of Tamoxifen Versus Z-Endoxifen HCL in Postmenopausal Women with Metastatic; Estrogen Receptor Positive; HER2 Negative Breast Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|A011202||Alliance||A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|A011106||Alliance||ALTernate approaches for clinical stage II or III Estrogen Receptor positive breast cancer NeoAdjuvant TrEatment (ALTERNATE) in postmenopausal women: A Phase III Study||Adult CIRB - Late Phase Emphasis||Available to Open|
|9984||ETCTN||A Randomized Phase 2 Study of cediranib in Combination with olaparib versus olaparib alone in men with metastatic castration resistant prostate cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|9979||ETCTN||Phase 1 and Pharmacology Study of Oral 5-iodo-2-pyrimidinone-2-deoxyribose (IPdR) as a Prodrug for IUdR-Mediated Tumor Radiosensitization in Brain Metastases||Adult CIRB - Early Phase Emphasis||Available to Open|
|9974||ETCTN||A phase II study of olaparib plus cediranib in combination with standard therapy for small cell lung cancer||Adult CIRB - Early Phase Emphasis||Completed|
|9952||ETCTN||Phase 1 Trial to Determine the Recommended Phase 2 Dose (RP2D) of VX-970 When Combined with Whole Brain Radiotherapy (WBRT) in Patients with Brain Metastases from Non-Small Cell Lung Cancer (NSCLC)||Adult CIRB - Early Phase Emphasis||Available to Open|