Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NSABP-B-47||NSABP||A Randomized Phase III Trial of Adjuvant Therapy Comparing Chemotherapy Alone (Six Cycles of Docetaxel Plus Cyclophosphamide or Four Cycles of Doxorubicin Plus Cyclophosphamide Followed by Weekly Paclitaxel) to Chemotherapy Plus Trastuzumab in Women with Node-Positive or High-Risk Node-Negative HER2-Low Invasive Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|NSABP-B-38||NSABP||A Phase III; Adjuvant Trial Comparing Three Chemotherapy Regimens in Women with Node-Positive Breast Cancer: Docetaxel/Doxorubicin/Cyclophosphamide (TAC); Dose-Dense (DD) Doxorubicin/Cyclophosphamide Followed by DD Paclitaxel (DD AC->P); DD AC Followed by DD Paclitaxel Plus Gemcitabine (DD AC->PG)||Adult CIRB - Late Phase Emphasis||Completed|
|RTOG-1005||RTOG||A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0436||RTOG||A Phase III Trial Evaluating the Addition of Cetuximab to Paclitaxel; Cisplatin; and Radiation for Patients with Esophageal Cancer who are Treated without Surgery||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0724||RTOG||Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-BR-0118||RTOG||A Phase III Study of Conventional Radiation Therapy Plus Thalidomide (NSC# 66847) Versus Conventional Radiation Therapy For Multiple Brain Metastases||Adult CIRB - Late Phase Emphasis||Completed|
|RTOG-0214||RTOG||A Phase III Comparison of Prophylactic Cranial Irradiation Versus Observation in Patients With Locally Advanced Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|RTOG-1010||RTOG||A Phase III Trial Evaluating the Addition of Trastuzumab to Trimodality Treatment of HER2-Overexpressing Esophageal Adenocarcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0521||RTOG||A Phase III Protocol of Androgen Suppression (AS) and 3DCRT/IMRT vs. AS and 3DCRT/IMRT followed by Chemotherapy with Docetaxel and Prednisone for Localized; High-Risk Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0815||RTOG||A Phase III Prospective Randomized Trial of Dose-Escalated Radiotherapy With or Without Short-Term Androgen Deprivation Therapy for Patients With Intermediate-Risk Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|