Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|9846||ETCTN||Patient-Derived Models Tissue Procurement Protocol For The National Cancer Institute (NCI)||Adult CIRB - Early Phase Emphasis||Available to Open|
|NRG-HN003||NRG||A Phase I and Expansion Cohort Study of Adjuvant Cisplatin; Intensity-Modulated Radiotherapy; and MK-3475 (Pembrolizumab) in High-Risk Head and Neck Squamous Cell Carcinoma (HNSCC)||Adult CIRB - Early Phase Emphasis||Available to Open|
|ADVL1513||COG||A Phase 1 Study of Entinostat; An Oral Histone Deacetylase Inhibitor; In Pediatric Patients with Recurrent or Refractory Solid Tumors; Including CNS Tumors and Lymphoma||Pediatric CIRB||Available to Open|
|10021||ETCTN||A Phase 2 Study of MEDI4736(durvalumab) and Tremelimumab Alone or in Combination with High or Low-Dose Radiation in Metastatic Colorectal and NSCLC||Adult CIRB - Early Phase Emphasis||Available to Open|
|10132||ETCTN||A Phase I Study of the Wee 1 kinase (Wee 1) inhibitor AZD1775 in combination with Radiotherapy and Cisplatin in Cervical, Upper Vaginal and Uterine Cancers||Adult CIRB - Early Phase Emphasis||Available to Open|
|EA3132||ECOG-ACRIN||Phase II Randomized Trial of Adjuvant Radiotherapy with or Without Cisplatin for p53 Mutated; Surgically Resected Squamous Cell Carcinoma of the Head and Neck (SCCHN)||Adult CIRB - Late Phase Emphasis||Available to Open|
|A041703||Alliance||Phase II Study of Inotuzumab Ozogamicin Followed by Blinatumomab for Ph-Negative CD22-Positive B-Lineage Acute Lymphoblastic Leukemia in Newly Diagnosed Older Adults or Adults with Relapsed or Refractory Disease||Adult CIRB - Late Phase Emphasis||Available to Open|
|E4412||ECOG-ACRIN||A Phase I Study with an Expansion Cohort/Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Hodgkin Lymphoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|ARET0332||COG||A Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|UAZ2016-08-02||CLO-University of Arizona||A feasibility trial of alternating intravaginal application of 5-fluorouracil and imiquimod for treatment of high-grade cervical squamous intraepithelial lesions||Cancer Prevention and Control CIRB||Available to Open|