Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|ANBL17P1||COG||A Pilot Induction Regimen Incorporating Chimeric 14.18 Antibody (ch14.18, dinutuximab) (NSC# 764038, IND# 4308) and Sargramostim (GM-CSF) for the Treatment of Newly Diagnosed High-Risk Neuroblastoma||Pediatric CIRB||Available to Open|
|ANHL1131||COG||Intergroup Trial for Children or Adolescents with B-Cell NHL or B-AL: Evaluation of Rituximab Efficacy and Safety in High Risk Patients||Pediatric CIRB||Available to Open|
|S0307||SWOG||Phase III Trial of Bisphosphonates as Adjuvant Therapy for Primary Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA2142||ECOG-ACRIN||Randomized Phase II Study of Platinum and Etoposide versus Temozolomide and Capecitabine in Patients with Advanced G3 Non-Small Cell Gastroenteropancreatic Neuroendocrine Carcinomas||Adult CIRB - Early Phase Emphasis||Available to Open|
|UAZ2016-08-02||CLO-University of Arizona||A feasibility trial of alternating intravaginal application of 5-fluorouracil and imiquimod for treatment of high-grade cervical squamous intraepithelial lesions||Cancer Prevention and Control CIRB||Available to Open|
|A221805||Alliance||Duloxetine to Prevent Oxaliplatin-Induced Chemotherapy-Induced Peripheral Neuropathy: A Randomized, Double-Blind, Placebo-Controlled Phase II to Phase III Study||Cancer Prevention and Control CIRB||Available to Open|
|AAML0431||COG||The Treatment of Down Syndrome Children with Acute Myeloid Leukemia (AML) and Myelodysplastic Syndrome (MDS) Under the Age of 4 Years: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|ACCL16N1CD||COG||Documentation and Delivery of Guideline-Consistent Treatment in Adolescent and Young Adult (AYA) Acute Lymphoblastic Leukemia (ALL)||Pediatric CIRB||Available to Open|
|A221504||Alliance||A Randomized; Double-Blind; Placebo-Controlled Pilot Study of an Oral; Selective Peripheral Opioid Receptor Antagonist in Advanced Non-Small Cell Lung Cancer (Adenocarcinoma)||Cancer Prevention and Control CIRB||Available to Open|
|ADVL1513||COG||A Phase 1 Study of Entinostat; An Oral Histone Deacetylase Inhibitor; In Pediatric Patients with Recurrent or Refractory Solid Tumors; Including CNS Tumors and Lymphoma||Pediatric CIRB||Available to Open|