Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|AOST06P1||COG||Feasibility and Dose Discovery Analysis of Zoledronic Acid with Concurrent Chemotherapy in the Treatment of Newly Diagnosed Metastatic Osteosarcoma: A Groupwide Pilot Study||Pediatric CIRB||Completed|
|ALTE07C1||COG||Neuropsychological; Social; Emotional; and Behavioral Outcomes in Children with Cancer: A Groupwide Non-Therapeutic Study||Pediatric CIRB||Available to Open|
|AGCT1531||COG||A Phase 3 Study of Active Surveillance for Low risk and a Randomized Trial of Carboplatin vs. Cisplatin for Standard Risk Pediatric and Adult Patients with Germ Cell Tumors||Pediatric CIRB||Available to Open|
|ACNS0333||COG||Treatment of Atypical Teratoid/Rhabdoid Tumors (AT/RT) of the Central Nervous System with Surgery; Intensive Chemotherapy; and 3-D Conformal Radiation: A Phase III Group-Wide Study||Pediatric CIRB||Available to Open|
|AALL1732||COG||A Phase 3 Randomized Trial of Inotuzumab Ozogamicin (IND#:133494, NSC#: 772518) for Newly Diagnosed High-Risk B-ALL; Risk-Adapted Post-Induction Therapy for High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and Disseminated B-LLy||Pediatric CIRB||Available to Open|
|ACNS1221||COG||A Phase II Study For The Treatment Of Non-Metastatic Nodular Desmoplastic Medulloblastoma In Children Less Than 4 Years Of Age: A Groupwide Phase II Study||Pediatric CIRB||Available to Open|
|ALTE1621||COG||Pharmacologic Reversal of Ventricular Remodeling in Childhood Cancer Survivors at Risk for Heart Failure (PREVENT-HF): A Phase 2b Randomized Placebo-Controlled (Carvedilol) Trial||Pediatric CIRB||Available to Open|
|ADVL1622||COG||Phase 2 Trial of XL184 (Cabozantinib); an Oral Small-Molecule Inhibitor of Multiple Kinases; in Children and Young Adults with Refractory Sarcomas; Wilms Tumor; and Other Rare Tumors||Pediatric CIRB||Available to Open|
|ACCL04C2||COG||Randomized Study of Electroacupuncture Treatment for Delayed Chemotherapy-induced Nausea and Vomiting in Patients with Pediatric Solid Tumors 02-AT-0172||Pediatric CIRB||Completed|
|AALL1131||COG||A Phase III Randomized Trial for Newly Diagnosed High Risk B-Lymphoblastic Leukemia (B-ALL) Including a Stratum Evaluating Dasatinib (IND#73789; NSC#732517) in Patients with Ph-like Tyrosine Kinase Inhibitor (TKI) Sensitive Mutations||Pediatric CIRB||Available to Open|