Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|ACNS0222||COG||A Phase II Study of Motexafin-Gadolinium (NSC #695238; IND #55583) and Involved Field Radiation Therapy for Intrinsic Pontine Glioma of Childhood: A Groupwide Phase II Study||Pediatric CIRB||Completed|
|RTOG-P-0011||RTOG||Phase III Randomized Study of Adjuvant Therapy For High Risk PT2-3N0 Prostate Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|CALGB-30102||CALGB||Phase III Comparison of Catheter Based Therapy of Pleural Effusions in Cancer Patients (Optimal Pleural Effusion Control; OPEC||Adult CIRB - Late Phase Emphasis||Completed|
|GOG-0241||GOG||A GCIG Intergroup Multicenter Phase III Trial of Open Label Carboplatin and Paclitaxel +/- NCI-Supplied Agent: Bevacizumab (NSC #704865; IND #113912) Compared With Oxaliplatin and Capecitabine +/- Bevacizumab as First Line Chemotherapy in Patients with Mucinous Epithelial Ovarian or Fallopian Tube Cancer (MEOC)||Adult CIRB - Late Phase Emphasis||Completed|
|AHOD0521||COG||A Phase II Study of Bortezomib (Velcade; PS-341; IND # 58443) in Combination with Ifosfamide/Vinorelbine in Pediatric Patients and Young Adults with Refractory/Recurrent Hodgkin Disease: A Groupwide Phase II Study||Pediatric CIRB||Completed|
|ADVL0921||COG||A Phase II Study of MLN8237 (IND# 102984); a Selective Aurora A Kinase Inhibitor in Children with Recurrent/Refractory Solid Tumors and Leukemias||Pediatric CIRB||Completed|
|S0502||SWOG||A Phase III Randomized Study of Imatinib; with or without Bevacizumab (NSC-704865); in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors NCT #00324987||Adult CIRB - Late Phase Emphasis||Completed|
|10130||ETCTN||A phase I study of single agent tazemetostat in subjects with advanced solid tumors and B-cell lymphomas with hepatic dysfunction||Adult CIRB - Early Phase Emphasis||Completed|
|10050||ETCTN||A Phase II Study of Selumetinib (AZD6244) for the Treatment of Advanced Pancreas Cancer harboring KRAS G12R Mutations||Adult CIRB - Early Phase Emphasis||Completed|
|ACOSOG-Z4032||ACSOG||A Randomized Phase III Study of Sublobar Resection versus Sublobar Resection Plus Brachytherapy in High Risk Patients with Non-Small Cell Lung Cancer (NSCLC); 3 cm or Smaller||Adult CIRB - Late Phase Emphasis||Completed|