CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 671 - 680 of 730
Study Number Lead Group Study Title CIRB Study Status
10219 ETCTN Phase I Dose-Escalation and Dose-Expansion Trial of a Novel Glutaminase Inhibitor (CB-839 HCl) in Combination with Carfilzomib and Dexamethasone in Relapsed and/or Refractory Multiple Myeloma Adult CIRB - Early Phase Emphasis Available to Open
10218 ETCTN A Phase 1b Trial of CB-839 in Combination with Radiation Therapy and Temozolomide in Patients with IDH-mutated Diffuse Astrocytoma and Anaplastic Astrocytoma Adult CIRB - Early Phase Emphasis Available to Open
10216 ETCTN A Phase I/II Study of AZD9291 (Osimertinib) and CB-839 HCl in Patients with EGFR Mutant Non-Small Cell Lung Cancer Adult CIRB - Early Phase Emphasis Available to Open
10214 ETCTN Immune Checkpoint Blockade for Kidney Transplant Recipients with Selected Unresectable or Metastatic Cancers Adult CIRB - Early Phase Emphasis Available to Open
10212 ETCTN A Phase 1b/2 study of Pinometostat in Combination with standard induction chemotherapy in newly diagnosed Acute Myeloid Leukemia with MLL rearrangement Adult CIRB - Early Phase Emphasis Available to Open
10208 ETCTN A Phase I study of Anetumab Ravtansine in Combination with either Anti-PD-1 Antibody, or Anti-CTLA4 and Anti-PD-1 Antibodies or Anti-PD-1 Antibody and Gemcitabine in Mesothelin-Positive Advanced Pancreatic Adenocarcinoma Adult CIRB - Early Phase Emphasis Available to Open
10204 ETCTN A Phase 1b Study of Nivolumab in Patients with Autoimmune Disorders and Advanced Malignancies (AIM-NIVO) Adult CIRB - Early Phase Emphasis Available to Open
10200 ETCTN Combination Pinometostat and 5-Azacitidine for the Treatment of Patients with Relapsed / Refractory Acute Myeloid Leukemia, or Newly Diagnosed Patients Who are Ineligible for or Unwilling to Undergo Intensive Therapy, Who Harbor an 11q23 Rearrangement Adult CIRB - Early Phase Emphasis Available to Open
10195 ETCTN A Phase 2 Study of Copanlisib (BAY 80-6946) in Combination with Fulvestrant in Women with Metastatic Breast Cancer Progressing After Aromatase Inhibitor Plus CDK 4/6 Inhibitor Adult CIRB - Early Phase Emphasis Available to Open
10193 ETCTN Phase 2 Study of Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-cell Lymphoma and Primary Mediastinal Large B-cell Lymphoma Adult CIRB - Early Phase Emphasis Available to Open
Displaying 671 - 680 of 730