CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 661 - 670 of 730
Study Number Lead Group Study Title CIRB Study Status
9149 ETCTN Molecular Profiling-based Assignment of Cancer Therapy for Patients With Advanced Solid Tumors Adult CIRB - Late Phase Emphasis Available to Open
8329 ETCTN A Phase I/II Trial of ABT-888, an Inhibitor of Poly(ADP-ribose) Polymerase (PARP), and Topotecan (TPT) in Patients with Solid Tumors (Phase I) and Relapsed Ovarian Cancer or Primary Peritoneal Cancer (Phase II) After Prior Platinum Containing First-Line Chemotherapy Adult CIRB - Early Phase Emphasis Available to Open
7977 ETCTN A Phase I Dose-Escalation Study of Oral ABT-888 (NSC #737664) Plus Intravenous Irinotecan (CPT-11, NSC#616348) Administered in Patients with Advanced Solid Tumors Adult CIRB - Early Phase Emphasis Available to Open
10292 ETCTN DURVA+ : Evaluation of the Safety and Pharmacodynamics of Anti-PD-L1 Antibody MEDI4736 (durvalumab) in Combination with Chemotherapy in Patients with Advanced Solid Tumors Adult CIRB - Early Phase Emphasis Available to Open
10250 ETCTN A Phase II Study of the PARP Inhibitor Olaparib in Combination with the DNA Damaging Agent Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma Adult CIRB - Early Phase Emphasis Available to Open
10249 ETCTN MLN9708 (Ixazomib) and MLN4924 (Pevonedistat) in Relapsed/Refractory Multiple Myeloma Patients: A Phase 1b Trial Adult CIRB - Early Phase Emphasis Available to Open
10247 ETCTN A Randomized Phase II Trial of MLN4924 (Pevonedistat) with Azacitidine versus Azacitidine in Adult Relapsed or Refractory Acute Myeloid Leukemia Adult CIRB - Early Phase Emphasis Available to Open
10246 ETCTN A Phase 1 Study of MLN4924 (pevonedistat) and Belinostat in Relapsed/Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome Adult CIRB - Early Phase Emphasis Available to Open
10240 ETCTN Phase II Study of XL184 (cabozantinib) in combination with Nivolumab and Ipilimumab (CaboNivoIpi) in Patients with Radioiodine-refractory Differentiated Thyroid Cancer whose Cancer Progressed after One Prior VEGFR-Targeted Therapy Adult CIRB - Early Phase Emphasis Available to Open
10231 NCI NCORP Tissue Procurement Protocol: An NCI Cancer Moonshot Study Adult CIRB - Late Phase Emphasis Available to Open
Displaying 661 - 670 of 730