CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| NRG-GI003 | NRG | Phase III Randomized Trial of Protons versus Photons for Hepatocellular Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI004 | NRG | Colorectal Cancer Metastatic dMMR Immuno-Therapy (COMMIT) Study: A Randomized Phase III Study of mFOLFOX6/Bevacizumab Combination Chemotherapy with or without Atezolizumab or Atezolizumab Monotherapy in the First-Line Treatment of Patients with Deficient DNA Mismatch Repair (dMMR) Metastatic Colorectal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI005 | NRG | Phase II/III Study of Circulating tumOr DNA as a Predictive BiomaRker in Adjuvant Chemotherapy in Patients with Stage IIA Colon Cancer (COBRA) | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI006 | NRG | Phase III Randomized Trial of Proton Beam Therapy (PBT) versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GI007 | NRG | Phase I Trial with Expansion Cohort of OBP-301 (Telomelysin™) and Definitive Chemoradiation for Patients with Locally Advanced Esophageal and Gastroesophageal Adenocarcinoma Who Are Not Candidates for Surgery | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU001 | NRG | Randomized Phase II Trial of Postoperative Adjuvant IMRT Following Cystectomy for pT3/pT4 Urothelial Bladder Cancer | Adult CIRB - Late Phase Emphasis | Completed |
| NRG-GU002 | NRG | Phase II-III Trial of Adjuvant Radiotherapy and Androgen Deprivation following Radical Prostatectomy with or without Adjuvant Docetaxel | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU003 | NRG | A Randomized Phase III Trial of Hypofractionated Post-Prostatectomy Radiation Therapy (HYPORT) versus Conventional Post-Prostatectomy Radiation Therapy (COPORT) | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU005 | NRG | Phase III IGRT and SBRT vs IGRT and Hypofractionated IMRT for Localized Intermediate Risk Prostate Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| NRG-GU006 | NRG | A Phase II, Double-Blinded, Placebo-Controlled Randomized Trial of Salvage Radiotherapy with or without Enhanced Anti-Androgen Therapy with Apalutamide in Recurrent Prostate Cancer (BALANCE*) *Biomarker trial of ApaLutamide and rAdiation for recurreNt prostate CancEr | Adult CIRB - Late Phase Emphasis | Available to Open |