Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|PBTC-049||PBTC||A Pediatric Brain Tumor Consortium Phase I/II and Surgical Study of CX-4945 in Patients with Recurrent SHH Medulloblastoma||Pediatric CIRB||Available to Open|
|9824||ETCTN||A Phase 1 Study of alisertib (MLN8237) in combination with mFOLFOX in gastrointestinal tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|ACNS0334||COG||A Phase III Randomized Trial for the Treatment of Newly Diagnosed Supratentorial PNET and High Risk Medulloblastoma in Children < 36 months Old with Intensive Induction Chemotherapy with Methotrexate Followed by Consolidation with Stem Cell Rescue vs. the Same Therapy Without Methotrexate: A Phase III Group-Wide Study||Pediatric CIRB||Available to Open|
|NRG-GY017||NRG||Anti PD-L1 (Atezolizumab) as an Immune Primer and Concurrently with Extended Field Chemoradiotherapy for Node Positive Locally Advanced Cervical Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|RTOG-0522||RTOG||A Randomized Phase III Trial of Concurrent Accelerated Radiation and Cisplatin Versus Concurrent Accelerated Radiation; Cisplatin and Cetuximab (C225) [Followed by Surgery for Selected Patients] For Stage III and IV Head and Neck Carcinomas<br>||Adult CIRB - Late Phase Emphasis||Available to Open|
|WF-10217||NCORP-Wake Forest University||Work Ability in Young Adult Survivors (WAYS)||Cancer Prevention and Control CIRB||Available to Open|
|CALGB-40503||CALGB||Endocrine Therapy with or without ANTI-VEGF Therapy: A Randomized; Phase III Trial of Endocrine Therapy Alone or Endocrine Therapy Plus Bevacizumab (NSC 704865; IND 7921) for Women with Hormone Receptor-Positive Advanced Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|ARET0332||COG||A Study of Unilateral Retinoblastoma With and Without Histopathologic High-Risk Features and the Role of Adjuvant Chemotherapy: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|EAZ171||ECOG-ACRIN||Prospective validation trial of taxane therapy (docetaxel or weekly paclitaxel) and risk of chemotherapy-induced peripheral neuropathy in African American women||Cancer Prevention and Control CIRB||Available to Open|
|10056||ETCTN||A Phase 2 Study of Talimogene Laherparepvec (T-VEC) and Radiation in Localized Soft Tissue Sarcoma||Adult CIRB - Early Phase Emphasis||Available to Open|