Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|EAF151||ECOG-ACRIN||Change in Relative Cerebral Blood Volume as a Biomarker for Early Response to Bevacizumab in Patients with Recurrent Glioblastoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|A211601||Alliance||Evaluation of Mammographic Breast Density Effect of Aspirin: A companion study to Alliance Study A011502||Cancer Prevention and Control CIRB||Available to Open|
|AALL08P1||COG||Intensified PEG-Asparaginase in High Risk Acute Lymphoblastic Leukemia (ALL): A Pilot Study||Pediatric CIRB||Available to Open|
|CALGB-10201||CALGB||A Phase III Study of Daunorubicin and Cytarabine +\- G3139 (GenasenseTM; Oblimersen Sodium; NSC #683428; IND #58842); A BCL2 Antisense Oligodeoxynucleotide; in Previously Untreated Patients with Acute Myeloid Leukemia (AML) > 60 Years||Adult CIRB - Late Phase Emphasis||Available to Open|
|NSABP-B-55||NSABP||A Randomised; Double-blind; Parallel group; Placebo-controlled Multi-centre Phase III Study to Assess the Efficacy and Safety of Olaparib Versus Placebo as Adjuvant Treatment in Patients with Germline BRCA1/2 mutations and High Risk HER2 Negative Primary Breast Cancer Who Have Completed Definitive Local Treatment and Neoadjuvant or Adjuvant Chemotherapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|E1A06||ECOG||An Intergroup Phase III Randomized Controlled Trial Comparing Melphalan; Prednisone and Thalidomide (MPT) Versus Melphalan; Prednisone and Lenalidomide (Revlimid TM) (MPR) in Newly Diagnosed Multiple Myeloma Patients Who Are Not Candidates for High-Dose Therapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|10139||ETCTN||A Randomized Phase 2 Study of Atezolizumab in Combination with Cobimetinib versus Atezolizumab Monotherapy in Participants with Unresectable Cholangiocarcinoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|N107C||NCCTG||A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease||Adult CIRB - Late Phase Emphasis||Available to Open|
|AOST06B1||COG||A Children's Oncology Group Protocol for Collecting and Banking Osteosarcoma Specimens||Pediatric CIRB||Available to Open|
|S1806||SWOG||Phase III Randomized Trial of Concurrent Chemoradiotherapy with or without Atezolizumab in Localized Muscle Invasive Bladder Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|