CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

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Study Number Lead Group Study Title CIRB Study Status
10355 ETCTN A phase I study of DS-8201a in combination with olaparib in HER2-expressing malignancies Adult CIRB - Early Phase Emphasis Available to Open
RTOG-0129 RTOG A Phase III Trial of Concurrent Radiation and Chemotherapy (Followed by Surgery for Residual Primary/N2-3 Nodal Disease) for Advanced Head and Neck Carcinomas Adult CIRB - Late Phase Emphasis Available to Open
CALGB-80802 CALGB Phase III Randomized Study of Sorafenib Plus Doxorubicin Versus Sorafenib in Patients with Advanced Hepatocellular Carcinoma (HCC) Adult CIRB - Late Phase Emphasis Available to Open
9984 ETCTN A Randomized Phase 2 Study of cediranib in Combination with olaparib versus olaparib alone in men with metastatic castration resistant prostate cancer Adult CIRB - Early Phase Emphasis Available to Open
A011202 Alliance A Randomized Phase III Trial Comparing Axillary Lymph Node Dissection to Axillary Radiation in Breast Cancer Patients (cT1-3 N1) Who Have Positive Sentinel Lymph Node Disease After Neoadjuvant Chemotherapy Adult CIRB - Late Phase Emphasis Available to Open
NWU2015-06-02 CLO-Northwestern University Immunogenicity of Nonavalent HPV Vaccine Administered Prior To Renal Transplantation in Adults: A Prospective, Single-Arm, Multi-Center Clinical Trial Cancer Prevention and Control CIRB Available to Open
CITN-14 CITN A Randomized Phase II Study of Atezolizumab (MPDL3280A) plus Recombinant Human IL-7 (CYT107) in patients with locally advanced or metastatic urothelial carcinoma Adult CIRB - Early Phase Emphasis Available to Open
RTOG-0924 RTOG Androgen Deprivation Therapy and High Dose Radiotherapy With or Without Whole-Pelvic Radiotherapy in Unfavorable Intermediate or Favorable High Risk Prostate Cancer: A Phase III Randomized Trial Adult CIRB - Late Phase Emphasis Available to Open
A221504 Alliance A Randomized, Double-Blind, Placebo-Controlled Pilot Study of an Oral, Selective Peripheral Opioid Receptor Antagonist in Advanced Non-Small Cell Lung Cancer Cancer Prevention and Control CIRB Available to Open
NWU2016-08-02 CLO-Northwestern University A Phase I Single-Arm, Multicenter Pilot Study Aimed at Validating Gamma-OHPdG as a Biomarker and Testing the Effects of Polyphenon E® on its Levels in Patients with Cirrhosis Cancer Prevention and Control CIRB Available to Open
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