Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|10030||ETCTN||A phase 1 study of blinatumomab in combination with checkpoint inhibitor(s) of PD-1 (nivolumab) or both PD-1 (nivolumab) and CTLA-4 (ipilimumab) in patients with poor-risk; relapsed or refractory CD19+ precursor B-lymphoblastic leukemia||Adult CIRB - Early Phase Emphasis||Available to Open|
|UAZ2017-09-02||CLO-University of Arizona||Clinical Study of Avmacol® for Detoxification of Tobacco Carcinogens in Heavy Smokers||Cancer Prevention and Control CIRB||Available to Open|
|AREN0533||COG||Treatment of Newly Diagnosed Higher Risk Favorable Histology Wilms Tumors: A Groupwide Phase III Study||Pediatric CIRB||Available to Open|
|UAZ2015-05-01||CLO-University of Arizona||A prospective, single-arm, open-label, non-randomized, phase IIA trial of a nonavalent prophylactic HPV vaccine to assess immunogenicity of a prime and deferred-booster dosing schedule among 9-11 year-old girls and boys||Cancer Prevention and Control CIRB||Available to Open|
|RTOG-1115||RTOG||Phase III Trial of Dose Escalated Radiation Therapy and Standard Androgen Deprivation Therapy (ADT) with a GnRH Agonist vs. Dose Escalated Radiation Therapy and Enhanced ADT with a GnRH Agonist and TAK-700 For Men with High Risk Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|10216||ETCTN||A Phase I/II Study of AZD9291 (Osimertinib) and CB-839 HCl in Patients with EGFR Mutant Non-Small Cell Lung Cancer||Adult CIRB - Early Phase Emphasis||Available to Open|
|NRG-GI005||NRG||Phase II/III Study of Circulating tumOr DNA as a Predictive BiomaRker in Adjuvant Chemotherapy in Patients with Stage IIA Colon Cancer (COBRA)||Adult CIRB - Late Phase Emphasis||Available to Open|
|A021806||Alliance||A Phase III Trial of Perioperative versus Adjuvant Chemotherapy for Resectable Pancreatic Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|NHLBI-MDS||ECOG||The National Myelodysplastic Syndromes (MDS) Study||Cancer Prevention and Control CIRB||Available to Open|
|PBTC-051||PBTC||Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma||Pediatric CIRB||Available to Open|