CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| S1400ANCILLARY | SWOG | Ancillary Study to Evaluate Patient and Physician Attitudes; Knowledge; and Expectations Related to Return of Genomic Results in Cancer in the SWOG 1400 (S1400) Clinical Trial | Adult CIRB - Late Phase Emphasis | |
| ACOSOG-Z1041 | ACSOG | A Randomized Phase III Trial Comparing a Neoadjuvant Regimen of FEC-75 Followed by Paclitaxel Plus Trastuzumab With a Neoadjuvant Regimen of Paclitaxel Plus Trastuzumab Followed by FEC-75 Plus Trastuzumab in Patients with HER-2 Positive Operable Breast Cancer | Adult CIRB - Late Phase Emphasis | Available to Open |
| ANZGOG-0902-GOG-0274 | GOG | A Phase III Trial of Adjuvant Chemotherapy Following Chemoradiation as Primary Treatment for Locally Advanced Cervical Cancer Compared to Chemoradiation Alone: THE OUTBACK TRIAL (ANZGOG 0902/GOG-0274/RTOG 1174) | Adult CIRB - Late Phase Emphasis | Available to Open |
| AHOD03P1 | COG | Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study | Pediatric CIRB | Available to Open |
| E4412 | ECOG-ACRIN | A Phase I Study with an Expansion Cohort/Randomized Phase II Study of the Combinations of Ipilimumab, Nivolumab and Brentuximab Vedotin in Patients with Relapsed/Refractory Hodgkin Lymphoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| S1505 | SWOG | A Randomized Phase II Study of Perioperative mFOLFIRINOX versus Gemcitabine/NAB-Paclitaxel as Therapy for Resectable Pancreatic Adenocarcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| 9673 | ETCTN | A Multi-Institutional Phase II Study of Nivolumab in Refractory Metastatic Squamous Cell Carcinoma of the Anal Canal | Adult CIRB - Early Phase Emphasis | Available to Open |
| ACCL15N1CD | COG | Use of Evidence-Based Supportive Care Clinical Practice Guidelines in Pediatric Oncology | Pediatric CIRB | Available to Open |
| EA6174 | ECOG-ACRIN | A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma | Adult CIRB - Late Phase Emphasis | Available to Open |
| RTOG-1308 | RTOG | Phase III Randomized Trial Comparing Overall Survival After Photon Versus Proton Chemoradiotherapy For Inoperable Stage II-IIIB NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |