CIRB Studies
Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
| Study Number | Lead Group | Study Title | CIRB | Study Status |
|---|---|---|---|---|
| GOG-0275 | GOG | A Phase III Randomized Trial of Pulse Actinomycin-D Versus Multi-Day Methotrexate for the Treatment of Low-Risk Gestational Trophoblastic Neoplasia | Adult CIRB - Late Phase Emphasis | Available to Open |
| UAZ2017-09-02 | CLO-University of Arizona | Clinical Study of Avmacol® for Detoxification of Tobacco Carcinogens in Heavy Smokers | Cancer Prevention and Control CIRB | Available to Open |
| PBTC-055 | PBTC | Phase I/II trial of Dabrafenib, Trametinib, and Hydroxychloroquine (HCQ) for BRAF V600E-mutant or Trametinib and HCQ for BRAF fusion/duplication positive or NF1-associated recurrent or progressive gliomas in children and young adults | Pediatric CIRB | Available to Open |
| 10410 | ETCTN | A Phase 1 Study of IPdR in Combination with Capecitabine and Radiotherapy in Rectal Cancer | Adult CIRB - Early Phase Emphasis | Available to Open |
| ADVL1521 | COG | A Phase 2 Study of the MEK inhibitor Trametinib (IND #119346, NSC# 763093) in Children with Relapsed or Refractory Juvenile Myelomonocytic Leukemia | Pediatric CIRB | Available to Open |
| EA5152 | ECOG-ACRIN | A Randomized Phase II Trial of Nivolumab, Cabozantinib Plus Nivolumab, and Cabozantinib Plus Nivolumab Plus Ipilimumab in Patients with Previously Treated Non-Squamous NSCLC | Adult CIRB - Late Phase Emphasis | Available to Open |
| ALTE03N1 | COG | Key Adverse Events after Childhood Cancer | Pediatric CIRB | Available to Open |
| NRG-LU005 | NRG | Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab | Adult CIRB - Late Phase Emphasis | Available to Open |
| ACCL1131 | COG | A Phase III Open-Label Trial of Caspofungin vs. Azole Prophylaxis for Patients at High-Risk for Invasive Fungal Infections (IFI) Following Allogeneic Hematopoietic Cell Transplantation (HCT) | Pediatric CIRB | Available to Open |
| NRG-BR001 | RTOG | A Phase 1 Study of Stereotactic Body Radiotherapy (SBRT) for the Treatment of Multiple Metastases | Adult CIRB - Early Phase Emphasis | Available to Open |