Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NSABP-NCIC-CTG-MA.32.F||NSABP||Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|B-31 dbGAP||NSABP||Comparison of methods for development of predictive signatures for therapy selection||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-LU001||NRG||Randomized Phase II Trial of Concurrent Chemoradiotherapy +/- Metformin HCL in Locally Advanced NSCLC||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0724||RTOG||Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy||Adult CIRB - Late Phase Emphasis||Available to Open|
|GOG-0201||GOG||Treatment of Patients with Stage IB2 Carcinoma of the Cervix: A Randomized Comparison of Radical Hysterectomy and Tailored Chemoradiation VERSUS Primary Chemoradiation||Adult CIRB - Late Phase Emphasis||Completed|
|NRG-GI006||NRG||Phase III Randomized Trial of Proton Beam Therapy (PBT) versus Intensity Modulated Photon Radiotherapy (IMRT) for the Treatment of Esophageal Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0521||RTOG||A Phase III Protocol of Androgen Suppression (AS) and 3DCRT/IMRT vs. AS and 3DCRT/IMRT followed by Chemotherapy with Docetaxel and Prednisone for Localized; High-Risk Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|S0347||SWOG||A Randomized Study of Weekly Vinorelbine (Navelbine) Alone or in Combination with Trastuzumab (Herceptin) (NSC-688097) for Patients with HER-2-Positive Metastatic Breast Cancer Whose Tumors Have Progressed After Taxane + Trastuzumab Combination Therapy - Phase III||Adult CIRB - Late Phase Emphasis||Completed|
|CALGB-30506||CALGB||A Randomized Phase III Trial of Adjuvant Chemotherapy in Patients with Early Stage Non-Small Cell Lung Cancer Associated with Banking of Frozen Tumor Specimens and Collection of Gene Expression Profile Data||Adult CIRB - Late Phase Emphasis||Completed|
|NCIC-BR.19||NCIC CTG||A Phase III Prospective Randomized; Double-Blind; Placebo-Controlled Trial of the Epidermal Growth Factor Receptor Antagonist; ZD1839 (IRESSA) in Completely Resected Primary Stage IB; II and IIIA Non-Small Cell Lung Cancer||Adult CIRB - Late Phase Emphasis||Completed|