Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|N1048||NCCTG||A Phase II/III Trial of Neoadjuvant FOLFOX; with Selective Use of Combined Modality Chemoradiation versus Preoperative Combined Modality Chemoradiation for Locally Advanced Rectal Cancer Patients Undergoing Low Anterior Resection with Total Mesorectal Excision||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-90203||CALGB||A Randomized Phase III Study of Neo-Adjuvant Docetaxel and Androgen Deprivation Prior to Radical Prostatectomy Versus Immediate Radical Prostatectomy in Patients with High-Risk; Clinically Localized Prostate Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-GI003||NRG||Phase III Randomized Trial of Protons versus Photons for Hepatocellular Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0421||RTOG||A Phase III Trial for Locally Recurrent; Previously Irradiated Head and Neck Cancer: Concurrent Re-Irradiation and Chemotherapy Versus Chemotherapy Alone.||Adult CIRB - Late Phase Emphasis||Completed|
|S0502||SWOG||A Phase III Randomized Study of Imatinib; with or without Bevacizumab (NSC-704865); in Patients with Metastatic or Unresectable Gastrointestinal Stromal Tumors NCT #00324987||Adult CIRB - Late Phase Emphasis||Completed|
|E5204||ECOG||Intergroup Randomized Phase III Study of Postoperative Oxaliplatin; 5-Fluorouracil; and Leucovorin vs Oxaliplatin; 5-Fluorouracil; Leucovorin and Bevacizumab for Patients with Stage II or III Rectal Cancer Receiving Pre-Operative Chemoradiation||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA6174||ECOG-ACRIN||A Phase III Randomized Trial Comparing Adjuvant MK-3475 (Pembrolizumab) to Standard of Care Observation in Completely Resected Merkel Cell Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-40502||CALGB||A Randomized Phase III Trial of Weekly Paclitaxel Compared to Weekly Nanoparticle Albumin Bound Nab-Paclitaxel or Ixabepilone With or Without Bevacizumab as First-Line Therapy for Locally Recurrent or Metastatic Breast Cancer<br>||Adult CIRB - Late Phase Emphasis||Available to Open|
|CALGB-80101||CALGB||Phase III Intergroup Trial of Adjuvant Chemoradiation After Resection of Gastric or Gastroesophageal Adenocarcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-HN001||RTOG||Randomized Phase II and Phase III Studies of Individualized Treatment for Nasopharyngeal Carcinoma Based on Biomarker Epstein Barr Virus (EBV) Deoxyribonucleic Acid (DNA)||Adult CIRB - Late Phase Emphasis||Available to Open|