Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|A021502||Alliance||Randomized Trial of FOLFOX Alone or Combined with Atezolizumab as Adjuvant Therapy for Patients with Stage III Colon Cancer and Deficient DNA Mismatch Repair or Microsatellite Instability (ATOMIC*)||Adult CIRB - Late Phase Emphasis||Available to Open|
|NRG-HN002||NRG||A Randomized Phase II Trial for Patients with p16 Positive; Non-Smoking Associated; Locoregionally Advanced Oropharyngeal Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA5161||ECOG-ACRIN||Randomized Phase II Clinical Trial of Cisplatin/Carboplatin and Etoposide (CE) alone or in Combination with Nivolumab as Frontline Therapy for Extensive Stage Small Cell Lung Cancer (ED-SCLC)||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-P-0011||RTOG||Phase III Randomized Study of Adjuvant Therapy For High Risk PT2-3N0 Prostate Cancer||Adult CIRB - Late Phase Emphasis||Completed|
|S1613||SWOG||A Randomized Phase II Study of Trastuzumab and Pertuzumab (TP) Compared to Cetuximab and Irinotecan (CETIRI) in Advanced/Metastatic Colorectal Cancer (MCRC) with HER-2 Amplification||Adult CIRB - Late Phase Emphasis||Available to Open|
|E5202||ECOG||A Randomized Phase III Study Comparing 5-FU; Leucovorin and Oxaliplatin Versus 5-FU; Leucovorin; Oxaliplatin and Bevacizumab in Patients with Stage II Colon Cancer at High Risk for Recurrence to Determine Prospectively the Prognostic Value of Molecular Markers||Adult CIRB - Late Phase Emphasis||Available to Open|
|A091605||Alliance||A Randomized Phase II Study of anti-PD1 antibody [MK-3475 (pembrolizumab)] alone versus anti- PD1 antibody plus Stereotactic Body Radiation therapy in advanced Merkel Cell Carcinoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|N0574||NCCTG||Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients with One to Three Cerebral Metastases||Adult CIRB - Late Phase Emphasis||Available to Open|
|A041701||Alliance||A Randomized Phase II/III Study of Conventional Chemotherapy +/- Uproleselan (GMI-1271) in Older Adults with Acute Myeloid Leukemia Receiving Intensive Induction Chemotherapy||Adult CIRB - Late Phase Emphasis||Available to Open|
|NSABP-NCIC-CTG-MA.32.F||NSABP||Biobehavioral Mechanisms of Fatigue in Patients Treated on NCIC CTG MA.32: A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|