Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|NRG-LU005||NRG||Limited Stage Small Cell Lung Cancer (LS-SCLC): A Phase II/III Randomized Study of Chemoradiation Versus Chemoradiation Plus Atezolizumab||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA8153||ECOG-ACRIN||Cabazitaxel with Abiraterone versus Abiraterone alone Randomized Trial for Extensive Disease following Docetaxel: the CHAARTED2 Trial||Adult CIRB - Late Phase Emphasis||Available to Open|
|EA9181||ECOG-ACRIN||A Phase III Randomized Trial of Steroids +Tyrosine Kinase Inhibitor Induction with Chemotherapy or Blinatumomab for Newly Diagnosed BCR-ABL-positive Acute Lymphoblastic Leukemia in Adults||Adult CIRB - Late Phase Emphasis||Available to Open|
|10411||ETCTN||Phase 2 Study of Rogaratinib (BAY 1163877) in the Treatment of Patients with Sarcoma Harboring Alterations in Fibroblast Growth Factor Receptor (FGFR) 1-4 and SDH-deficient Gastrointestinal Stromal Tumor (GIST)||Adult CIRB - Early Phase Emphasis||Available to Open|
|RTOG-1005||RTOG||A Phase III Trial of Accelerated Whole Breast Irradiation with Hypofractionation plus Concurrent Boost Versus Standard Whole Breast Irradiation Plus Sequential Boost for Early-Stage Breast Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|10067||ETCTN||A randomized phase 2 trial of cediranib and olaparib compared to bevacizumab in patients with recurrent glioblastoma who have not received prior VEGF therapy||Adult CIRB - Early Phase Emphasis||Available to Open|
|A231602CD||Alliance||Assessing Financial Difficulty in Patients with Blood Cancers||Cancer Prevention and Control CIRB||Available to Open|
|9903||ETCTN||A Phase 1B Study of AZD9291 in Combination with Navitoclax in EGFR-mutant Non-Small Cell Lung Cancer Following Resistance to Initial EGFR Kinase Inhibitor||Adult CIRB - Early Phase Emphasis||Available to Open|
|AHOD03P1||COG||Treatment of Children with Newly-Diagnosed Low Stage Lymphocyte Predominant Hodgkin Disease (LPHD): A Groupwide Pilot Study||Pediatric CIRB||Available to Open|
|E2906||ECOG||Phase III Randomized Trial of Clofarabine as Induction and Post-Remission Therapy vs. Standard Daunorubicin & Cytarabine Induction and Intermediate Dose Cytarabine Post-Remission Therapy; Followed by Decitabine Maintenance vs. Observation in Newly-Diagnosed Acute Myeloid Leukemia in Older Adults (Age >/= 60 Years)||Adult CIRB - Late Phase Emphasis||Available to Open|