CIRB Studies

Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.

To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.

Displaying 1 - 10 of 888
Study Number Lead Group Study Title CIRB Study Status
A031704 Alliance PD-Inhibitor (Nivolumab) and Ipilimumab Followed by Nivolumab vs. VEGF TKI Cabozantinib with Nivolumab: A Phase III Trial in Metastatic Untreated Renal Cell Cancer [PDIGREE] Adult CIRB - Late Phase Emphasis Available to Open
AEWS1031 COG A Phase III Randomized Trial of Adding Vincristine-topotecan-cyclophosphamide to Standard Chemotherapy in Initial Treatment of Non-metastatic Ewing Sarcoma: A Groupwide Phase III Study Pediatric CIRB Available to Open
10075 ETCTN A Phase 1B Study of KRT-232 (AMG-232) in Combination with Decitabine in Acute Myeloid Leukemia Adult CIRB - Early Phase Emphasis Available to Open
RTOG-0724 RTOG Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy Adult CIRB - Late Phase Emphasis Available to Open
A081801 Alliance Integration of Immunotherapy into Adjuvant Therapy for Resected NSCLC: ALCHEMIST Chemo-IO Adult CIRB - Late Phase Emphasis Available to Open
NRG-HN007 NRG An Open-Label, Phase III Study of Platinum-Gemcitabine with or without Nivolumab in the First-Line Treatment of Recurrent or Metastatic Nasopharyngeal Carcinoma Adult CIRB - Late Phase Emphasis Available to Open
AOST1521 COG A Phase 2 Study of GPNMB-targeted Antibody-Drug Conjugate; CDX-011 (Glembatumumab Vedotin; CR011-vcMMAE; IND# 128248; NSC# 763737); in Recurrent or Refractory Osteosarcoma Pediatric CIRB Available to Open
A071401 Alliance Phase II Trial of SMO/AKT/NF2/CDK Inhibitors in Progressive Meningiomas with SMO/AKT/NF2/CDK Pathway Mutations Adult CIRB - Early Phase Emphasis Available to Open
NRG-GU006 NRG A Phase II, Double-Blinded, Placebo-Controlled Randomized Trial of Salvage Radiotherapy with or without Enhanced Anti-Androgen Therapy with Apalutamide in Recurrent Prostate Cancer (BALANCE*) *Biomarker trial of ApaLutamide and rAdiation for recurreNt prostate CancEr Adult CIRB - Late Phase Emphasis Available to Open
10193 ETCTN Phase 2 Study of Copanlisib in Combination with Nivolumab in Subjects with Relapsed/Refractory Diffuse Large B-cell Lymphoma and Primary Mediastinal Large B-cell Lymphoma Adult CIRB - Early Phase Emphasis Available to Open
Displaying 1 - 10 of 888