Below is the current list of studies covered by the CIRB. It includes both Available to Open and Completed studies. Study documents approved after July 1, 2013 for all covered studies are available on the CTSU website.
To request documents approved before July 1, 2013, please contact the CIRB Helpdesk.
|Study Number||Lead Group||Study Title||CIRB||Study Status|
|S1400ANCILLARY||SWOG||Ancillary Study to Evaluate Patient and Physician Attitudes; Knowledge; and Expectations Related to Return of Genomic Results in Cancer in the SWOG 1400 (S1400) Clinical Trial||Adult CIRB - Late Phase Emphasis|
|EA6141||ECOG-ACRIN||Randomized Phase II/III Study of Nivolumab plus Ipilimumab plus Sargramostim versus Nivolumab plus Ipilimumab in Patients with Unresectable Stage III or Stage IV Melanoma||Adult CIRB - Late Phase Emphasis||Available to Open|
|10250||ETCTN||A Phase II Study of the PARP Inhibitor Olaparib in Combination with the DNA Damaging Agent Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma||Adult CIRB - Early Phase Emphasis||Available to Open|
|10222||ETCTN||A Phase II study of olaparib and AZD6738 in isocitrate dehydrogenase (IDH) mutant solid tumors||Adult CIRB - Early Phase Emphasis||Available to Open|
|PBTC-051||PBTC||Phase I Study to Evaluate the Safety and Tolerability of the CD40 Agonistic Monoclonal Antibody APX005M in Pediatric Subjects with Recurrent/Refractory Brain Tumors and Newly Diagnosed Brain Stem Glioma||Pediatric CIRB||Available to Open|
|9874||ETCTN||A Phase I Trial of AT13387 in Patients with Locoregionally Advanced Squamous Cell Carcinoma of the Head and Neck (LA-SCCHN) receiving Concurrent Radiation and Cisplatin||Adult CIRB - Early Phase Emphasis||Available to Open|
|10170||ETCTN||A Phase 2 Study of AZD1775 in SETD2-Deficient Advanced Solid Tumor Malignancies||Adult CIRB - Early Phase Emphasis||Available to Open|
|GOG-0209||GOG||Randomized Phase III Trial of Doxorubicin/Cisplatin/Paclitaxel and G-CSF Versus Carboplatin/Paclitaxel in Patients with Stage III & IV or Recurrent Endometrial Cancer||Adult CIRB - Late Phase Emphasis||Available to Open|
|RTOG-0724||RTOG||Phase III Randomized Study of Concurrent Chemotherapy and Pelvic Radiation Therapy with or without Adjuvant Chemotherapy in High-Risk Patients with Early-Stage Cervical Carcinoma Following Radical Hysterectomy||Adult CIRB - Late Phase Emphasis||Available to Open|
|ANBL0931||COG||A Comprehensive Safety Trial of Chimeric Antibody 14.18 (ch14.18) with GM-CSF; IL-2 and Isotretinoin in High-Risk Neuroblastoma Patients Following Myeloablative Therapy: A Limited Institution Study||Pediatric CIRB||Available to Open|